Results 81 to 90 of about 849,758 (304)

N-Site approximations and CAM analysis for a stochastic sandpile

open access: yes, 2002
I develop n-site cluster approximations for a stochastic sandpile in one dimension. A height restriction is imposed to limit the number of states: each site can harbor at most two particles (height z_i \leq 2).
A. Chessa   +34 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Standardization of 3D printing parameters to control the size and shape of pores in Polylactic acid scaffolds

open access: yesMedComm – Biomaterials and Applications
The challenge of three‐dimensional (3D) printing by polymeric extrusion in tissue bioengineering is to control with precision the microarchitecture and porous interconnectivity of scaffolds, as well as search for models that allow and facilitate the ...
Lucía Pérez‐Sánchez   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Geometric determinants of sinterless, low-temperature-processed 3D-nanoprinted glass

open access: yesMicrosystems & Nanoengineering
Glass materials are essential for microsystems applications in fields ranging from optics and photonics to microfluidics and biomedicine, which has driven growing interest in additive manufacturing—or “three-dimensional (3D) printing”—to enable glass ...
Adira Colton   +12 more
doaj   +1 more source

Critical bending point in the Lyapunov localization spectra of many-particle systems

open access: yes, 2005
The localization spectra of Lyapunov vectors in many-particle systems at low density exhibit a characteristic bending behavior. It is shown that this behavior is due to a restriction on the maximum number of the most localized Lyapunov vectors determined
Benettin   +32 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quark pseudoscalar vertex and quark mass function with clover fermions : spontaneous symmetry breaking, OPE, symmetry restoration at small volume

open access: yes, 2010
We study the quark mass function on hypercubic lattices, in a large range of physical volumes and cutoffs. To avoid the very large Wilson term artefact, we exploit the relation between the quark mass function and the pseudoscalar vertex in the continuum.
A. Le Yaouanc   +7 more
core   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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