Results 111 to 120 of about 12,108,841 (318)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Monocular reading performance measured by MNREAD-P acuity chart in normo-readers schoolchildren
Scientific ReportsThis study aimed to determine and establish values for reading performance in normo-readers schoolchildren. Literate students aged 8 to 18 years old without visual impairments were recruited. The MNREAD-P chart was used to assess monocular reading acuity
Yan Jonathan D’Almeida Souza +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The Relationship Between Back Pain and Sedentary Lifestyles and Sports Among University Students
Studia Universitatis Babeş-Bolyai: Educatio Artis GymnasticaeIntroduction: Back pain is increasingly prevalent among university students and is commonly associated with sedentary behavior, prolonged sitting, and lifestyle-related risk factors.
Karola SZŐCS +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Revista Diálogo EducacionalThis article aims to analyz the edition of the Primeiro Catecismo da Doutrina Cristã (First Catechism of Christian Doctrine) published by the Vozes publishing house in 1964 which presents significant alterations in relation to editions published in ...
Aline Marie De Simone +2 more
doaj +1 more source
Journal of Medical Internet Research, 2011 BackgroundResearchers and practitioners have developed numerous online interventions that encourage people to reduce their drinking, increase their exercise, and better manage their weight.
Cugelman, Brian +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source