Results 81 to 90 of about 847,794 (302)

Standardization of 3D printing parameters to control the size and shape of pores in Polylactic acid scaffolds

open access: yesMedComm – Biomaterials and Applications
The challenge of three‐dimensional (3D) printing by polymeric extrusion in tissue bioengineering is to control with precision the microarchitecture and porous interconnectivity of scaffolds, as well as search for models that allow and facilitate the ...
Lucía Pérez‐Sánchez   +5 more
doaj   +1 more source

Metal-insulator transition in the one-dimensional Holstein model at half filling

open access: yes, 1999
We study the one-dimensional Holstein model with spin-1/2 electrons at half-filling. Ground state properties are calculated for long chains with great accuracy using the density matrix renormalization group method and extrapolated to the thermodynamic ...
A. Takahashi   +48 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Geometric determinants of sinterless, low-temperature-processed 3D-nanoprinted glass

open access: yesMicrosystems & Nanoengineering
Glass materials are essential for microsystems applications in fields ranging from optics and photonics to microfluidics and biomedicine, which has driven growing interest in additive manufacturing—or “three-dimensional (3D) printing”—to enable glass ...
Adira Colton   +12 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Regional gene therapy with 3D printed scaffolds to heal critical sized bone defects in a rat model

open access: yesJournal of Biomedical Materials Research Part A, 2019
AbstractThe objective of the present study was to assess the ability of transduced rat bone marrow cells (RBMCs) that overexpress BMP‐2 loaded on a three‐dimensionally (3D) printed scaffold to heal a critical sized rat femoral defect. Tricalcium phosphate (TCP) scaffolds were 3D printed to fit a critical sized rat femoral defect.
Ram, Alluri   +9 more
openaire   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Online Interventions for Social Marketing Health Behavior Change Campaigns: A Meta-Analysis of Psychological Architectures and Adherence Factors

open access: yesJournal of Medical Internet Research, 2011
BackgroundResearchers and practitioners have developed numerous online interventions that encourage people to reduce their drinking, increase their exercise, and better manage their weight.
Cugelman, Brian   +2 more
doaj   +1 more source

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