Results 121 to 130 of about 11,231,749 (288)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Other title: Connecticut Council on Developmental Disabilities
, 2016 Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 11/14/16Official website of the Connecticut State Properties Review Board. Provides
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Critical thresholds in soil physical properties driven by microplastics
Microplastics and NanoplasticsBackground Growing evidence suggests that many ecological systems exhibit tipping points, thresholds at which small changes in stressors can trigger critical shifts in ecosystem properties.
Tamara Meizoso-Regueira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Evidence-based teaching: A critical overview for enquiring teachers.
, 2018 This book provides a critical overview of evidence-based teaching, with balanced and reflective consideration given to arguments supporting various approaches to increasing the use of evidence in teaching and arguments that raise doubts about, or ...
Poultney, Val, Philpott, Carey
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Prestellar Cores in Turbulent Clouds: Properties of Critical Cores
The Astrophysical JournalA fraction of the dense cores within a turbulent molecular cloud will eventually collapse to form stars. Identifying the physical criteria for instability and analyzing critical core properties is therefore necessary to star formation theory.
Sanghyuk Moon, Eve C. Ostriker
doaj +1 more source
Critical properties of the SIS model on the clustered homophilic network. [PDF]
Physica A, 2020 Santos FL +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source