Results 101 to 110 of about 1,419,653 (264)

Critical thresholds in soil physical properties driven by microplastics

open access: yesMicroplastics and Nanoplastics
Background Growing evidence suggests that many ecological systems exhibit tipping points, thresholds at which small changes in stressors can trigger critical shifts in ecosystem properties.
Tamara Meizoso-Regueira   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Prestellar Cores in Turbulent Clouds: Properties of Critical Cores

open access: yesThe Astrophysical Journal
A fraction of the dense cores within a turbulent molecular cloud will eventually collapse to form stars. Identifying the physical criteria for instability and analyzing critical core properties is therefore necessary to star formation theory.
Sanghyuk Moon, Eve C. Ostriker
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Critical properties of the SIS model on the clustered homophilic network. [PDF]

open access: yesPhysica A, 2020
Santos FL   +5 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Computation Thermodynamic Properties of SuperheatedWater* Far from Critical Region

open access: yesJournal of Engineering and Sustainable Development, 2011
A general equation has been presented in the present work to calculate specific volume, internal energy, enthalpy and entropy of superheated steam. The developed equation appeared in one context in order to confer upon it the status of generalizing form
Tawfeeq Kadheem Faleh Al-Hamdi
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Universal Properties of Critical Mixed-States from Measurement and Feedback

open access: yesPRX Quantum
We explore the universal properties of mixed quantum matter obtained from “single-shot” adaptive evolution, in which a quantum-critical ground-state is manipulated through a single round of local measurements and local unitary operations conditioned on ...
Zhehao Zhang   +3 more
doaj   +1 more source

Effects of Methyl Terminal and Carbon Bridging Groups Ratio on Critical Properties of Porous Organosilicate-Glass Films. [PDF]

open access: yesMaterials (Basel), 2020
Vishnevskiy AS   +9 more
europepmc   +1 more source

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