Results 81 to 90 of about 11,231,749 (288)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Diversity of Collembola on Various Post-Rehabilitation Land Covers

open access: yesJurnal Manajemen Hutan Tropika
The success of rehabilitation has altered environmental conditions from critical land to new habitats for living organisms. One of the representative and sensitive mesofauna to environmental changes is Collembola.
Risandika Astanovia Dewi   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

EFFECT OF IMPELLER BLADE THICKNESS ON CRITICAL IMPELLER SPEED IN AN AGITATED VESSEL

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2017
The successful design and operation of solid-liquid agitators require proper prediction of critical impeller speed (Njs) needed to suspend solids. It depends on system and impeller geometry as well as the properties of both solid and liquid.
LOGANATHAN MURUGANANDAM   +1 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Connecticut Council on Developmental Disabilities

open access: yes, 2011
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/26/11Official website of the Connecticut State Properties Review Board.

core  

Construction and validation of an Instrument for the evaluation of Critical Thinking in Family Leisure Decision offline and online (ICT_FLD)

open access: yesRED. Revista de Educación a Distancia
Families' critical thinking about shared leisure, both offline and online, influences the quality of family dynamics and the socio-educational development of children.
Natalia González-Fernández   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Other title: Connecticut Council on Developmental Disabilities

open access: yes, 2015
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 11/19/15Official website of the Connecticut State Properties Review Board. Provides

core  

Critical literacy : the Four Resources model & (teaching) reading

open access: yes, 2019
Reading, from a critical literacy perspective, requires that teachers and learners make meaning beyond the text: from decoding, to comprehension, to critical language awareness. Where decoding is related to the technical skills of reading (linking sounds
Govender, Navan
core   +2 more sources

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