Results 121 to 130 of about 11,999,161 (302)

Critical appraisal --- The response

open access: yesAnnals of Maxillofacial Surgery, 2018
Garg, Ritesh, Alexander, Mohan
openaire   +3 more sources

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The Case for Heat Acclimatization of Disaster Responders—An Australian Perspective

open access: yesFrontiers in Public Health, 2017
Matt B. Brearley   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Research Review: Effect of the critical care outreach team on patient survival to discharge from hospital and readmission to critical care: non-randomised population based study

open access: yes, 2004
While many descriptive studies about the UK model for critical care outreach have been published recently1, this publication documents a rigorous implementation and evaluation plan for determining the effect of a critical care outreach team in one ...
Chaboyer, Wendy
core   +1 more source

The role of nitric oxide synthase in biofilm formation by Staphylococcus aureus

open access: yesnpj Biofilms and Microbiomes
Staphylococcus aureus is capable of colonizing diverse environments and forming biofilms. In this study, we found that the knockout of NO synthase (NOS) impaired biofilm integrity, resulting in weakened biofilms.
Yi Huang   +8 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Critical Health Communication

open access: yes
This book offers strong rationales for adopting a critical view of health communication by demonstrating how theories and critical practices can be enriched by foregrounding issues of power, politics, and culture.

core   +1 more source

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