Results 191 to 200 of about 11,999,161 (302)

Critical care readiness in conflict and disaster-affected Somalia: mass-casualty response, emergency referral, and continuity of life-saving care special collection: critical care in war and disaster areas. [PDF]

Crit Care
Siyad AO, Hassan AM.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Author Response: Comment on-Practice Pattern of Critical Care Ultrasonography in India (POCUS India)/A Multicenter Cross-sectional Survey. [PDF]

Indian J Crit Care Med
Pal D, Govil D.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Real-world use and evaluation of a generative AI chatbot for Parkinson's disease information: a prospective observational study. [PDF]

Lancet Reg Health Eur
Lange F, Mardi S, Binder T, Reich MM, Odorfer T, Volkmann J.   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Publisher Correction: A chronic whole cigarette smoke extract model reveals redox–mitochondrial adaptation in human lung epithelial and organoid models

Experimental and Molecular Medicine
Joo-Eun Lee, Dahye Lee, Jihyun Lee, Sung-Joon Han, Sung Hyun Kang, Ryeo-Eun Go, Jihyun Kwon, Younjhin Ahn, Mi Jung Lim, Mahn Jae Lee, Hee Min Yoo, Da Hyun Kang, Jeong Eun Lee, Dongil Park, Chaeuk Chung   +14 more
doaj   +1 more source

Strengthening anesthesia capacity in war and disaster areas: a critical care priority. [PDF]

Crit Care
Asowe HA.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Cardiac index modifies the association between blood pressure response index and 28-day mortality in sepsis. [PDF]

Crit Care
Lei R, Ye C, Yue C, Yan Q, Wang X, Ma Q, Hu C, Yue F, Yang M.   +8 more
europepmc   +1 more source