Results 61 to 70 of about 589,600 (262)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Physiological Performance Measures as Indicators of CrossFit® Performance
CrossFit® began as another exercise program to improve physical fitness and has rapidly grown into the “sport of fitness„. However, little is understood as to the physiological indicators that determine CrossFit® sport performance ...
Joshua D. Dexheimer +5 more
doaj +1 more source
On Critical Speeds Induced by Ball Bearings in Lower Rotating Speeds
When single-row radial ball bearings are used, several critical speeds take place in a vertical shaft at certain rotating speeds lower than the major critical speed. When the bearing center line of both bearing pedestals is not in alignment and the shaft is not in a perfectly straight line, there is the possibility that these critical speeds occur. The
openaire +3 more sources
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Driving vehicles on curved roads is dangerous because of the risk of accidents. This is due to the centrifugal force, gyroscopic moment and hydroplaning of the vehicle, ending with vehicle slipping or tipping.
Ibrahem A. Muhsin +1 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Highway Speed vs. Sideslip (Critical Speed in a Curve)
Is there a simple way to calculate vehicle speed based upon curved yaw marks on a road surface? J. Standard Baker, in his book Traffic Accident Investigation Manual, published by the Traffic Institute, Northwestern University, presents such a method.
openaire +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

