Results 81 to 90 of about 2,542,287 (293)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Review of research and development in fluid logic elements [PDF]
, 1967 Research and development in multistate fluid logic elements is reviewed in a historical and critical report. The report concludes that in the development of fluid amplifiers, there are elements with very high gain and poor switching speed, and other ...
Reader, T.
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Effective sound speed in relativistic accretion discs around rotating black holes
, 2019 For axially symmetric accretion maintained in the hydrostatic equilibrium along the vertical direction in the Kerr metric, the radial Mach number does not become unity at the critical point.
Das, Tapas Kumar +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Solitons in a hard-core bosonic system: Gross-Pitaevskii type and beyond
, 2014 A unified formulation that obtains solitary waves for various background densities in the Bose-Einstein condensate of a system of hard-core bosons with nearest neighbor attractive interactions is presented. In general, two species of solitons appear: A
Balakrishnan, Radha, Satija, Indubala I
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Nihon Kikai Gakkai ronbunshu, 2018 To investigate and understand conditions of mutual contact and collision impact between a wheel-flat and a roller rig, we first did a bench test of a bogie with the wheel flat on the roller rig.
Yasutaka MAKI, Yoshiaki TERUMICHI
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source