Results 101 to 110 of about 2,542,287 (293)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Analysis of the impact of rotor speed variations on the vibration of centrifugal compressor units
You-qi chuyunObjectiveThe rotor speed of operating centrifugal compressor units needs to be regulated according to working conditions and output requirements. Within the operational speed range, the rotors typically experience fluctuating vibrations in response to ...
Dongzhuo JIA +5 more
doaj +1 more source
On Critical Speeds Induced by Ball Bearings in Lower Rotating Speeds
Transactions of the Japan Society of Mechanical Engineers, 1957 When single-row radial ball bearings are used, several critical speeds take place in a vertical shaft at certain rotating speeds lower than the major critical speed. When the bearing center line of both bearing pedestals is not in alignment and the shaft is not in a perfectly straight line, there is the possibility that these critical speeds occur. The
openaire +3 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Modeling the expenditure and reconstitution of distance above critical speed during two swimming interval training sessions. [PDF]
Front Physiol, 2022 Raimundo JAG +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Critical speed estimated by statistically appropriate fitting procedures. [PDF]
Eur J Appl Physiol, 2021 Patoz A +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Research on Rotor Dynamic Characteristics of High Speed Aviation Piston Pump
LubricantsThe high-speed aviation piston pump plays a vital role in hydraulic systems in the aviation field. Extremely complex force situations happen during running operations due to the coupling between multiple components, as a result of the overall dynamic ...
Lijun Chen +5 more
doaj +1 more source