Results 121 to 130 of about 2,542,287 (293)
Peak Running Velocity or Critical Speed Under Field Conditions: Which Best Predicts 5-km Running Performance in Recreational Runners? [PDF]
Figueiredo DH +3 more
europepmc +1 more source
Eigenvalue assignment strategies in rotor systems [PDF]
The work done to establish the control and direction of effective eigenvalue excursions of lightly damped, speed dependent rotor systems using passive control is discussed.
Welzyn, K. J., Youngblood, J. N.
core +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The continuously supported rail subjected to an axial force and a moving load [PDF]
Axial compression force effects in welded rails on critical velocity for high speed ...
Kerr, A. D.
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Steady-state V ˙ O 2 above MLSS: evidence that critical speed better represents maximal metabolic steady state in well-trained runners. [PDF]
Nixon RJ +3 more
europepmc +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Critical Speed in a Curve - Update
V=(15 r f)l^(1/2)mph Where r is tire scuff radius of curvature in feet. f is the ratio of maximum lateral tire frictional force to vehicle weight. For the benefit of those readers unsure of the origin of the above equation, it is simply one possible solution to the undergraduate engineering dynamics text book problem involving a particle moving at ...
openaire +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source

