Results 91 to 100 of about 2,542,287 (293)

High stiffness seals for rotor critical speed control [PDF]

An annular seal is analyzed in which the inlet clearance is larger than the outlet clearance; the flow path may be either stepped or tapered. This design produces radial stiffness 1.7 to 14 times that of a constant clearance seal having the same minimum ...
Fleming, D. P.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Physiological Correspondence Between Different Indexes of High-Intensity Endurance Exercise in Young Male Runners

Sports
Critical speed (CS), the respiratory compensation point (RCP), and the midpoint between gas exchange threshold and maxial oxygen uptake (VO2max) (i.e., 50%Δ) have been considered indexes able to demarcate the boundary between the heavy and severe ...
Danilo A. Massini, Renato A. C. Caritá, Tiago A. F. Almeida, Anderson G. Macedo, Víctor Hernández-Beltrán, José M. Gamonales, Mário C. Espada, Dalton M. Pessôa Filho   +7 more
doaj   +1 more source

Towards Accurate Prediction of Unbalance Response, Oil Whirl and Oil Whip of Flexible Rotors Supported by Hydrodynamic Bearings

Lubricants, 2016
Journal bearings are used to support rotors in a wide range of applications. In order to ensure reliable operation, accurate analyses of these rotor-bearing systems are crucial.
Rob Eling, Mathys te Wierik, Ron van Ostayen, Daniel Rixen   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

DESIGN-STAGE ADJUSTMENT OF ROTOR CRITICAL SPEEDS

Вестник Донского государственного технического университета, 2018
Know-how and the computer-applied diversity algorithm (removal) for the operational and critical rotation speeds of the rotor at the design stage (critical frequencies adjustment) are offered.
Oleg O. Polushkin, Oleg A. Polushkin
doaj  

The Influence of Axial-Bearing Position of Active Magnetic Suspension Flywheel Energy Storage System on Vibration Characteristics of Flywheel Rotor

Actuators
This study introduces a flywheel rotor support structure for an active magnetic suspension flywheel energy storage system. In this structure, there is an axial offset between the axial-bearing position and the mass-center of the flywheel rotor, which ...
Lei Wang, Tielei Li, Zhengyi Ren
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Highway Speed vs. Sideslip (Critical Speed in a Curve)

Journal of the National Academy of Forensic Engineers, 1984
Is there a simple way to calculate vehicle speed based upon curved yaw marks on a road surface? J. Standard Baker, in his book Traffic Accident Investigation Manual, published by the Traffic Institute, Northwestern University, presents such a method.
openaire   +1 more source