Results 71 to 80 of about 1,504,011 (315)

Check-in Groups: A Novel Structured Crisis Intervention Model

, 2020
Crisis intervention teams, task forces, and healthcare coalitions are not new concepts. For over 20 years, theState of Indiana has hadan operational model of statewide emotional support and interventionteamswhich can be deployed to crisis events ...
Berman, David, Galyean, Erika, Richardson, Kimble   +2 more
core   +1 more source

The hypothesis of specific affinity of metabolic pathways inherent to onset of hibernation and reaction to critical stress stimuli [PDF]

Journal of Stress Physiology & Biochemistry, 2011
In this publication we are discussing the discovered analogy between reactions of hibernating and non-hibernating animals to critical factors in the external environment. A hypothesis is formulated regarding the mechanisms responsible for the discovered
Sokolova T.N.
doaj  

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The impacts of personal stress upon critical project decision making in construction

, 2010
The range of responsibilities for construction managers has become increasingly complex due to additional legal requirements and more widespread stakeholder involvements.
Blackhall, Ian, Littlemore, Michelle
core  

Managing stress in critical illness [PDF]

Critical Care Medicine, 2012
Physiological and emotional stress is a concomitant of critical illness regardless of its underlying cause, but our understanding of the influence of the stress response on clinical outcomes and how the response can be managed remains rudimentary.
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Interindividual differences in stress sensitivity: basal and stress-induced cortisol levels differentially predict neural vigilance processing under stress [PDF]

, 2016
Contains fulltext : 167313.pdf (Publisher’s version ) (Open Access)Stress exposure is known to precipitate psychological disorders. However, large differences exist in how individuals respond to stressful situations.
Kooijman, S.C., van Wingen, Guido A., Henckens, M.J.A.G., Everaerd, Daphne, Everaerd, D.S., Henckens, Marloes J. A. G., Kooijman, Sabine C., Fernández, Guillén, Fernandez, G.S.E., Klumpers, Floris, Wingen, G.A. van, Klumpers, F.   +11 more
core   +1 more source