Results 91 to 100 of about 1,504,011 (315)

Stress, coping and presenteeism in nurses assisting critical and potentially critical patients

open access: yesRevista da Escola de Enfermagem da USP, 2014
Objective to verify the associations between stress, Coping and Presenteeism in nurses operating on direct assistance to critical and potentially critical patients. Method this is a descriptive, cross-sectional and quantitative study, conducted between
Juliane Umann   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Exploratory study of managerial stress in Spain, An [PDF]

open access: yes
The purpose of this exploratory study is to chart the existing Spanish literature, and to report some first tentative results on managerial stress in Spain.
Cardona, Pablo   +2 more
core  

A novel weight function for RMS stress intensity factor determination in surface cracks [PDF]

open access: yes, 2010
This paper discusses the problem of stress intensity factor determination in surface cracks. In particular, the concept of root mean square stress intensity factors (RMS SIF) is discussed for the general class of semi-elliptical surface cracks.
Brennan, Feargal P.   +1 more
core   +1 more source

Ncl1-mediated metabolic rewiring critical during metabolic stress

open access: yesLife Science Alliance, 2019
Accumulation of cysteine induces translational defects and metabolic rewiring that are abrogated by leucine in a transfer RNA (tRNA) methyltransferase NCL1-dependent manner in yeast.
Ajay Bhat   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Early interventions following exposure to traumatic events: psychological debriefing and the law

open access: yes, 2003
Defines Post Traumatic Stress Disorder (PTSD) and discusses the advantages of providing "Critical Incident Stress Debriefing" (CISD) to those who have witnessed traumatic events to prevent them developing PTSD.
Wheat, K, Regel, S
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

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