Results 101 to 110 of about 1,504,011 (315)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Intensive care diaries reduce new onset post traumatic stress disorder following critical illness: a randomised, controlled trial

open access: yes, 2010
Patients recovering from critical illness have been shown to be at risk of developing Post Traumatic Stress disorder (PTSD). This study was to evaluate whether a prospectively collected diary of a patient's intensive care unit (ICU) stay when used during
Bäckman, Carl   +7 more
core  

Mature students' perception of stress on returning to learn [PDF]

open access: yes, 1996
In this thesis we present a theoretical model for mature students' perception of stress. The study examines the sources of institutional, dispositional and situational stress of students who are age thirty-to fifty-five.
Leger, E., Leger, Ellen
core  

Oxidative Stress in Critical Conditions and its Correction

open access: yesОбщая реаниматология, 2008
Severe postoperative complications and critical conditions caused by profuse hemorrhage, pulmonary thromboembolism, anaphylactic shock in response to drugs, as well as circulatory arrest, pyoseptic processes are accompanied by significant activation of ...
N. A. Osipova   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Stress-dilatancy Relation for Mohr-Coulomb Soils Following a Non-Associated Flow Rule

open access: yes, 2010
Rowe\u27s stress–dilatancy relation for frictional (cohesionless) materials has been a cornerstone of soil mechanics. The original derivation of this relationship was based on incorrect energy minimisation considerations, but the relationship was proven ...
Salgado, Rodrigo, Zhang, J
core   +1 more source

Finite deformation of particulate geomaterials: frictional and anisotropic Critical State elasto-plasticity [PDF]

open access: yes, 2011
This thesis is concerned with the theoretical development and numerical implementation of efficient constitutive models for the analysis of particulate media (specifically clays) in structures undergoing geometrically non-linear behaviour.
Coombs, W.M.   +2 more
core  

Ccl2‐Induced Regulatory T Cells Balance Inflammation Through Macrophage Polarization During Liver Reconstitution

open access: yesAdvanced Science
Inflammation is highlighted as an initial factor that helps orchestrate liver reconstitution. However, the precise mechanisms controlling inflammation during liver reconstitution have not been fully elucidated.
Rui Wang   +14 more
doaj   +1 more source

Transpulmonary LOX-1 Levels Are Predictive of Acute Respiratory Distress Syndrome After Cardiac Surgery: A Proof-of-Concept Study

open access: yesBiomedicines
Background/Objectives: Acute respiratory distress syndrome (ARDS) is a life-threatening condition that frequently complicates high-risk cardiac surgery. We evaluated the circulating levels and transpulmonary gradient of intracellular proteins in patients
Benjamin Deniau   +10 more
doaj   +1 more source

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