Results 181 to 190 of about 3,329,974 (215)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The State of Anesthesia and Critical Care Services in Somalia: Challenges and Opportunities. [PDF]

Risk Manag Healthc Policy
Mohamed IA, Garba B.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Innovative Blended Learning Curriculum in Noninvasive Ventilation for Pulmonary and Critical Care Fellows

Avicenna Journal of Medicine
Asil Daoud, Cassondra Cramer-Bour, Divya Venkat, Abdulghani Sankari   +3 more
doaj   +1 more source

Defining physician-AI collaboration in pulmonary and critical care medicine: concepts and illustrative examples for clinical reasoning. [PDF]

ATS Sch
Vaezi A, Ashby T, Kadir S, Schweitzer M, Hadeh A, Sen P, Seeram V, Mirsaeidi M.   +7 more
europepmc   +1 more source

FedCARE: Fuzzy-Supervised Federated Inference with Confidence Gating for Resilient IIoT Sensor Networks. [PDF]

Sensors (Basel)
Mostafa B, Haj Ahmad H, Rabaiah Y, Elseddik M.   +3 more
europepmc   +1 more source

Personality profiles and usage experience are associated with trust and dependence on generative AI: a latent profile analysis. [PDF]

Front Psychol
Zhang M, Zhao H, Wang Y.
europepmc   +1 more source

Life-Cycle Assessment of Nd-Fe-B Rare Earth Magnet Production. [PDF]

ACS Omega
Prados TM, Saragiotto Colpini LM, Alfonso Lovón-Canchumani G.   +2 more
europepmc   +1 more source

Extension of the Moore-Greitzer framework for accurate mathematical modelling of flow instabilities in a low-speed isolated axial compressor rotor blades row. [PDF]

Sci Rep
Katebi M, Zenouz RT.
europepmc   +1 more source

Comparative Usability Evaluation of Two Hospital Information Systems: A Mixed-Methods Study in an Iranian Teaching Hospital. [PDF]

Health Sci Rep
Mousavi AS, Jalili Honarvar E, Ardebili Haghighi A, Parveizi S, Granfar M, Mousavi Baigi SF.   +5 more
europepmc   +1 more source