Results 41 to 50 of about 657,159 (265)

From Critical Theory to Critical Hermeneutics

open access: yesNordicum-Mediterraneum, 2014
From their beginning in the 1930s, critical theory and the Frankfurt school had their focus on a critique of disturbed social relations in western society dominated by totalitarian political regimes like Stalinism, Fascism, Nazism, and by capitalism as ...
Øjvind Larsen
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Political Impact of Consumerism [PDF]

open access: yesTaḥqīqāt-i Farhangī-i Īrān, 2008
The main goal of this article is to study the outcomes of consumerism. The article mainly focuses on the political impact of consumerism. It also intends to analyze the role of television programs and advertisement to foster consumerism.
Fardin Alikhah
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Critical Theory of Law

open access: yesLegal Education Review, 1989
Many law professors consider their primary job to be teaching legal doctrine and legal skills. Students, they think, must learn how to find applicable legal rules and how to make the kind of arguments lawyers use in court.
Gerald E Frug
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

CRÍTICA DEL PENSAMIENTO CRÍTICO. APUNTES PARA PENSAR LAS LUCHAS

open access: yesRevista Latinoamericana de Derechos Humanos, 2015
Resumen El texto pretende establecer un diálogo a lo interno de la tradición crítica, y, por tanto, desde las preocupaciones de fondo que han marcado su quehacer.
Manuel E. Gándara Carballido.
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Death Drive and Critical Theory

open access: yesCritical Hermeneutics
Much has been said about death drive in Critical Theory. This concept was mainly read as an aggressive and/or destructive drive. As a consequence, there are two ways of finding death drive in critical theories: the classic mode represented by Adorno ...
Inara Luisa Marin
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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