Results 61 to 70 of about 613,272 (249)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
CRITICAL THEORY OF FRANKFURT SCHOOL
Kanz Philosophia: A Journal for Islamic Philosophy and MysticismThe present study aims to provide a comprehensive examination of the Frankfurt School’s Critical Theory, encompassing its historical origins, subsequent development, and the application of its values within educational contexts and the evolution of ...
Yudha Okta Anuhgra +2 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Reading, Writing and the “Straight White Male”: What Masculinity Studies Does to Literary Analysis
Angles, 2016 This article aims at mapping out some of the ways in which masculinity studies has recently renewed the critical approach to certain literary texts. It argues that this fairly new disciplinary field has helped to de-territorialize literary inquiry and ...
Pierre-Antoine Pellerin
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A brief reflection on the issue of science, ideology and critical theory. [PDF]
SSM Popul Health, 2021 Lindström M.
europepmc +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Bad or worse? Applying critical theory to explore the impacts of Payatas dumpsite closure on the former waste pickers. [PDF]
Waste Manag Res, 2023 Ito H, Igano C.
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Critical Theory, Culture Change, and Achieving Health Equity in Health Care Settings. [PDF]
Acad Med, 2022 Todic J +6 more
europepmc +1 more source