Results 71 to 80 of about 9,680,109 (207)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Hayes and Critical Theory - A Brief Rejoinder from James Page [PDF]
, 1986 James Page raises three objections to the suggestion from Mark Hayes that critical theory might serve as a theoretical basis for peace research: 1) the outmoded and questionable nature of critical theory, 2) the element of domination in the operation of ...
Page, James Smith
core
CRITICAL THEORY OF FRANKFURT SCHOOL
Kanz Philosophia: A Journal for Islamic Philosophy and MysticismThe present study aims to provide a comprehensive examination of the Frankfurt School’s Critical Theory, encompassing its historical origins, subsequent development, and the application of its values within educational contexts and the evolution of ...
Yudha Okta Anuhgra +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Critical theory and social inequality
Tempo SocialThis paper argues that social inequality is possibly the core topic of any critical theory in the social sciences – for epistemological as well as ethical reasons.
Boike Rehbein
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
CRITICAL THEORY AND E-EDUCATION
Metodički Vidici, 2014 There is an evident trend of an increased use of and positive attitudes towards e-Education and distance learning within the Croatian higher education system.
Josip T. Ćirić +1 more
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Reading, Writing and the “Straight White Male”: What Masculinity Studies Does to Literary Analysis
Angles, 2016 This article aims at mapping out some of the ways in which masculinity studies has recently renewed the critical approach to certain literary texts. It argues that this fairly new disciplinary field has helped to de-territorialize literary inquiry and ...
Pierre-Antoine Pellerin
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source