Results 71 to 80 of about 613,272 (249)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Critical Theory or Accepted Practice? Combining Careers in Critical Care Medicine and Gastroenterology. [PDF]
Dig Dis Sci, 2022 Saffo S, Leventhal TM.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Qu’est-ce que la critique dans la philosophie critique de la race ?
AstérionThe article takes the notion of critique seriously in order to evaluate to what extent, according to what characterisations, under what conditions, and with what limits critical philosophy of race (CPR), which refers to critical race theory specifically ...
Magali Bessone
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Metapresentiality: a foundational concept for a critical theory of digital health. [PDF]
Salud Colect, 2023 Almeida Filho N.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Bildung, capabilities, human freedom and human flourishing
Journal of Comparative Social WorkThere is international interest in approaches to social work focussing on human development and service users’ real freedoms to act. One such example, established in social work, is the capabilities approach.
Magnus Frampton +2 more
doaj +1 more source
The Criticism of Standard and the Standard of Criticism [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2017 Criticism is a natural and humane phenomenon, and it originates from human’s willingness to freedom. Thought is the mental moving from the base to the result and visa-versa. So, this action is subject to evaluation and criticism.
Gholamreza Fadaie
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source