Results 121 to 130 of about 7,950,057 (368)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Predicting Everyday Critical Thinking: A Review of Critical Thinking Assessments
Our ability to think critically and our disposition to do so can have major implications for our everyday lives. Research across the globe has shown the impact of critical thinking on decisions about our health, politics, relationships, finances ...
Heather A. Butler
doaj +1 more source
Critical Thinking Critical Thinking adds value
Research at Cambridge Assessment has found that there is a significant advantage to Critical Thinking (CT) candidates in their other subjects. Further research also investigated how CT is delivered in schools and found that despite a number of challenges and obstacles, teachers were convinced of the value of CT.
openaire +1 more source
Developing Critical Thinking Skills in Language Teaching: Oral Interpretation Class [PDF]
Critical Thinking Skill (CTS) is one of the skills that is required to survive in this globalization era. Peopleneed this skill to innovate in technology to increase education quality and to produce outstanding humanresources.
Junining, E. (Esti)
core
What have we been thinking of? A critical overview of 40 years of student learning research in higher education [PDF]
Tamsin Haggis
openalex +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A Research On The Critical Thinking Tendency of Nurse Managers
INTRODUCTION: The aim of this study is to determine the critical thinking trends of nurse managers working at Ministry of health training and research hospitals on the European side of İstanbul province and demographic characteristics of these trends ...
Muhteşem Baran, Fatma Balcı
doaj +1 more source
Thinking Creatively; Thinking Critically
The development of creative and critical thinking is seen as an encouragement to independent and student-centred learning. But what exactly do we mean when we talk about creative and critical thinking? When and why did these terms come into prominence in modern education?
openaire +2 more sources

