Results 101 to 110 of about 6,310,223 (297)

Promoting Critical Thinking in Anti-Critical Thinking Times: Lessons from COVID

open access: yesPhilosophical Inquiry in Education, 2022
We are witnessing what can only be called an anti-critical thinking trend in contemporary society. In this brief essay I want to describe how and why critical thinking is in crisis, and what that means for reconsidering the promotion of critical ...
Nicholas C. Burbules
doaj  

Developing critical thinking in NGO field staff

open access: yes, 2008
The quality of NGO work is hugely dependent on the quality of critical thinking and analysis of poverty among all levels of staff. In particular, the quality of the work in the field - at partner and community levels - depends on an understanding of ...
Foley, Connell
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Student Teacher and Lecturer Perceptions of the Use of Asynchronous Discussion Forums, Quizzes and Uploaded Resources for Promoting Critical Thinking [PDF]

open access: yes, 2014
This study examined student teacher and lecturer perceptions of the use of asynchronous discussion forums, quizzes and uploaded resources for promoting critical thinking within a pre-service teacher education programme in Tanzania.
Mwalongo, Alcuin Ivor
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Using Case Studies and Videotaped Vignettes to Facilitate the Development of Critical Thinking Skills in New Graduate Nurses [PDF]

open access: yes, 2012
Based on the increasing complexity of health care, nurses are performing extremely skilled and high level cognitive work that requires a solid foundation upon which to build.
Hooper, Barbara Louise
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Rhetoric and critical thinking

open access: yesDeeds and Days, 2016
The aim of this article is to show how rhetoric and critical thinking are intrinsically interrelated. I will explain why, in keeping with the history of the discipline itself, rhetoric can be a powerful tool for critical literacy. It can help raise our awareness of how social, political, ethical issues are always rhetorically constructed and why they ...
openaire   +4 more sources

An intervention program for practising critical thinking: on-shore and off-shore students blogging together [PDF]

open access: yes, 2009
An intervention program was devised to assist off-shore students develop critical thinking skills through blogs. On-shore students were assisted in setting up group blogs and off-shore students engaged in discussion with the issues raised. In this manner
Hobson, J.
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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