Results 131 to 140 of about 8,622,922 (338)

Critical Thinking Critical Thinking adds value

open access: yes, 2012
Research at Cambridge Assessment has found that there is a significant advantage to Critical Thinking (CT) candidates in their other subjects. Further research also investigated how CT is delivered in schools and found that despite a number of challenges and obstacles, teachers were convinced of the value of CT.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Critical Thinking and Legal Culture [PDF]

open access: yes
We often lack clear procedures for assessing statements and arguments advanced in everyday conversations, political campaigns, advertisements, and the other multifarious uses to which ordinary language can be put.
Guido Pincione
core  

Thinking Creatively; Thinking Critically

open access: yesAsian Social Science, 2009
The development of creative and critical thinking is seen as an encouragement to independent and student-centred learning.  But what exactly do we mean when we talk about creative and critical thinking? When  and why did these terms come into prominence in modern education?
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A Research On The Critical Thinking Tendency of Nurse Managers

open access: yesSağlık ve Hemşirelik Yönetimi Dergisi, 2017
INTRODUCTION: The aim of this study is to determine the critical thinking trends of nurse managers working at Ministry of health training and research hospitals on the European side of İstanbul province and demographic characteristics of these trends ...
Muhteşem Baran, Fatma Balcı
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Can students be taught to think critically? [PDF]

open access: yes, 2014
The literature on critical thinking has its roots in different disciplines – philosophy, psychology and education. These separate academic strands have led to the development of different definitions and therefore there has been little consensus on the ...
Ancill, Karen
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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