Results 151 to 160 of about 6,755,416 (402)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries.

open access: yesJournal of the American Medical Association (JAMA), 2021
V. Russotto   +22 more
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Prophylactic use of laxative for constipation in critically ill patients

open access: yesAnnals of Thoracic Medicine, 2010
Background : This study was designed to evaluate the use of laxative prophylaxis for constipation in intensive care unit (ICU) and the impact of early versus late bowel movement on patient′s outcome.
Masri Yasser   +2 more
doaj  

Acute Kidney Injury in Critically Ill Children [PDF]

open access: yes, 2015
__Abstract__ Acute kidney injury (AKI) (previously called acute renal failure) is characterized by the abrupt inability of the kidneys to adequately excrete waste products and regulate fl uid and electrolyte homeostasis appropriately.
Zwiers, A.J.M. (Alexandra)
core  

Evaluation of sepsis-induced coagulopathy in critically ill patients

open access: diamond, 2023
Helena Ostović   +3 more
openalex   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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