Results 11 to 20 of about 5,549,552 (344)
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
medRxiv, 2021 Background: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: We evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform ...A. Gordon, P. Mouncey, Farah Al-Beidh, K. Rowan, A. Nichol, Y. Arabi, D. Annane, A. Beane, Wilma van Bentum-Puijk, L. Berry, Zahra Bhimani, M. Bonten, C. Bradbury, F. Brunkhorst, Adrian Buzgau, A. Cheng, M. Detry, E. J. Duffy, L. Estcourt, M. Fitzgerald, H. Goossens, R. Haniffa, A. Higgins, T. Hills, Christopher M. Horvat, F. Lamontagne, P. Lawler, H. Leavis, K. Linstrum, E. Litton, E. Lorenzi, J. Marshall, F. Mayr, D. McAuley, A. McGlothlin, S. McGuinness, B. McVerry, S. Montgomery, S. Morpeth, S. Murthy, Katrina Orr, R. Parke, Jane C. Parker, A. Patanwala, V. Pettilä, E. Rademaker, Marlene S. Santos, Christina T. Saunders, C. Seymour, M. Shankar-Hari, W. Sligl, A. Turgeon, Anne M Turner, F. L. van de Veerdonk, R. Zarychanski, Cameron Green, R. Lewis, D. Angus, C. McArthur, S. Berry, S. Webb, L. Derde +61 moresemanticscholar +1 more sourceTherapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19
New England Journal of Medicine, 2021 Background Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid ...E. Goligher, C. Bradbury, B. McVerry, P. Lawler, J. Berger, M. Gong, M. Carrier, H. Reynolds, Ananda K Kumar, A. Turgeon, L. Kornblith, S. Kahn, J. Marshall, Keri S. Kim, Brett L. Houston, L. Derde, M. Cushman, T. Tritschler, D. Angus, L. C. Godoy, Z. McQuilten, B. Kirwan, M. Farkouh, M. Brooks, R. Lewis, L. Berry, E. Lorenzi, A. Gordon, S. Berry, C. McArthur, M. Neal, J. Hochman, S. Webb, R. Zarychanski, T. Ahuja, Farah Al-Beidh, D. Annane, Y. Arabi, Diptesh Aryal, Lisa Baumann Kreuziger, A. Beane, Zahra Bhimani, S. Bihari, H. Billett, Lindsay Bond, M. Bonten, F. Brunkhorst, M. Buxton, Adrian Buzgau, L. Castellucci, S. Chekuri, J. Chen, A. Cheng, T. Chkhikvadze, B. Coiffard, Aira Contreras, Todd W. Costantini, S. de Brouwer, M. Detry, A. Duggal, V. Džavík, M. Effron, H. Eng, J. Escobedo, L. Estcourt, Brendan M. Everett, D. Fergusson, M. Fitzgerald, R. Fowler, J. Froess, Zhuxuan Fu, J. Galanaud, B. Galen, S. Gandotra, T. Girard, A. Goodman, H. Goossens, Cameron Green, Y. Greenstein, P. Gross, R. Haniffa, Sheila M. Hegde, C. Hendrickson, A. Higgins, A. Hindenburg, A. Hope, J. Horowitz, Christopher M. Horvat, David T. Huang, Kristin M. Hudock, B. Hunt, M. Husain, R. Hyzy, J. Jacobson, Devachandran Jayakumar, N. Keller, Akram Khan, Yuri Kim, Andrei L. Kindzelski, A. King, M. Knudson, Aaron E. Kornblith, M. Kutcher, M. Laffan, F. Lamontagne, G. Le Gal, Christine M. Leeper, E. Leifer, G. Lim, Felipe Gallego Lima, K. Linstrum, E. Litton, J. López-Sendón, S. Lother, N. Marten, Andréa Saud Marinez, Mary Martinez, E. Mateos Garcia, Stavroula Mavromichalis, D. McAuley, E. McDonald, A. McGlothlin, S. McGuinness, S. Middeldorp, S. Montgomery, P. Mouncey, S. Murthy, G. Nair, Rahul R. Nair, A. Nichol, J. Nicolau, Brenda Nunez-Garcia, John J. Park, P. Park, R. Parke, Jane C. Parker, S. Parnia, J. Paul, M. Pompilio, J. Quigley, R. Rosenson, N. Rost, K. Rowan, F. O. Santos, Marlene S. Santos, M. O. Santos, L. Satterwhite, Christina T. Saunders, J. Schreiber, R. Schutgens, C. Seymour, D. Siegal, De Silva, A. Singhal, A. Slutsky, Dayna Solvason, S. Stanworth, Anne M Turner, Wilma van Bentum-Puijk, F. L. van de Veerdonk, S. van Diepen, Gloria Vázquez-Grande, Lana Wahid, Vanessa Wareham, R. Widmer, Jennifer G. Wilson, E. Yuriditsky, Yongqi Zhong +167 moresemanticscholar +1 more source2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility
Pediatric Critical Care Medicine, 2022 Supplemental Digital Content is available in the text. RATIONALE: A guideline that both evaluates current practice and provides recommendations to address sedation, pain, and delirium management with regard for neuromuscular blockade and withdrawal is ...Heidi A. B. Smith, J. Besunder, Kristina A. Betters, Peter N. Johnson, V. Srinivasan, A. Stormorken, E. Farrington, B. Golianu, A. Godshall, Larkin Acinelli, Christina Almgren, C. Bailey, Jenny M. Boyd, Michael J Cisco, M. Damian, M. Dealmeida, James Fehr, Kimberly E. Fenton, Frances Gilliland, M. Grant, Joy Howell, Cassandra A. Ruggles, Shari Simone, F. Su, J. Sullivan, K. Tegtmeyer, C. Traube, Stacey R. Williams, J. Berkenbosch +28 moresemanticscholar +1 more sourceEpidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study
medRxiv, 2020 Background: Nearly 30,000 patients with coronavirus disease-2019 (COVID-19) have been hospitalized in New York City as of April 14th, 2020. Data on the epidemiology, clinical course, and outcomes of critically ill patients with COVID-19 in this setting ...M. Cummings, M. Baldwin, D. Abrams, Samuel D. Jacobson, Benjamin J Meyer, Elizabeth M. Balough, J. Aaron, J. Claassen, L. Rabbani, J. Hastie, Beth Hochman, J. Salazar‐Schicchi, Natalie Yip, D. Brodie, M. O’Donnell +14 moresemanticscholar +2 more sourcesSurviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)
Critical Care Medicine, 2020 Supplemental Digital Content is available in the text. Background: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people ...W. Alhazzani, M. Møller, Y. Arabi, M. Loeb, M. Gong, E. Fan, S. Oczkowski, M. Levy, L. Derde, A. Dzierba, B. Du, M. Aboodi, H. Wunsch, M. Cecconi, Y. Koh, Daniel S. Chertow, K. Maitland, F. Alshamsi, E. Belley‐Cote, M. Greco, M. Laundy, Jill S. Morgan, J. Kesecioglu, A. McGeer, L. Mermel, M. Mammen, P. Alexander, A. Arrington, J. Centofanti, G. Citerio, Bandar Baw, Z. Memish, N. Hammond, F. Hayden, Laura Evans, A. Rhodes +35 moresemanticscholar +1 more sourceVideo versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults.
New England Journal of Medicine, 2023 BACKGROUND
Whether video laryngoscopy as compared with direct laryngoscopy increases the likelihood of successful tracheal intubation on the first attempt among critically ill adults is uncertain.
METHODS
In a multicenter, randomized trial conducted at M. Prekker, B. Driver, S. Trent, D. Resnick-Ault, K. Seitz, D. Russell, J. Gaillard, Andrew J. Latimer, S. Ghamande, K. Gibbs, D. Vonderhaar, M. Whitson, Christopher R. Barnes, J. Walco, I. Douglas, V. Krishnamoorthy, A. Dagan, Jill J. Bastman, B. D. Lloyd, S. Gandotra, Jordan K Goranson, S. Mitchell, H. White, J. Palakshappa, A. Espinera, D. Page, A. Joffe, Sydney J Hansen, C. Hughes, Tobias George, J. T. Herbert, N. Shapiro, S. Schauer, B. Long, B. Imhoff, Li Wang, J. Rhoads, K. Womack, D. Janz, W. Self, T. Rice, A. Ginde, J. Casey, M. Semler +43 moresemanticscholar +1 more sourceTreatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma.
Journal of the American Medical Association (JAMA), 2020 Importance
Coronavirus disease 2019 (COVID-19) is a pandemic with no specific therapeutic agents and substantial mortality. It is critical to find new treatments.Chenguang Shen, Zhaoqin Wang, Fang Zhao, Yang Yang, Jin-xiu Li, Jing Yuan, Fuxiang Wang, Delin Li, Minghui Yang, L. Xing, Jinli Wei, Haixia Xiao, Yan Yang, J. Qu, L. Qing, Li Chen, Zhixiang Xu, Ling Peng, Yanjie Li, Haixia Zheng, Feng Chen, Kun-Hua Huang, Yujing Jiang, Dongjing Liu, Zheng Zhang, Yingxia Liu, Lei Liu +26 moresemanticscholar +1 more sourceCovid-19 in Critically Ill Patients in the Seattle Region — Case Series
New England Journal of Medicine, 2020 Background Community transmission of coronavirus 2019 (Covid-19) was detected in the state of Washington in February 2020. Methods We identified patients from nine Seattle-area hospitals who were admitted to the intensive care unit (ICU) with confirmed ...P. Bhatraju, Bijan J. Ghassemieh, M. Nichols, R. Kim, Keith R. Jerome, Arun K. Nalla, A. Greninger, S. Pipavath, M. Wurfel, Laura Evans, Patricia A. Kritek, T. E. West, A. Luks, A. Gerbino, Chris R. Dale, Jason D. Goldman, Shane D. O'Mahony, C. Mikacenic +17 moresemanticscholar +1 more sourceAssociation Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.
Journal of the American Medical Association (JAMA), 2020 Importance
Effective therapies for patients with coronavirus disease 2019 (COVID-19) are needed, and clinical trial data have demonstrated that low-dose dexamethasone reduced mortality in hospitalized patients with COVID-19 who required respiratory ...J. Sterne, S. Murthy, Janet Diaz, Arthur S Slutsky, J. Villar, D. Angus, D. Annane, L. Azevedo, O. Berwanger, A. Cavalcanti, P. Dequin, B. Du, J. Emberson, D. Fisher, B. Giraudeau, A. Gordon, A. Granholm, Cameron Green, R. Haynes, Nicholas Heming, J. Higgins, P. Horby, P. Jüni, M. Landray, A. Le Gouge, M. Leclerc, W. Lim, F. Machado, C. McArthur, F. Meziani, M. Møller, A. Perner, M. W. Petersen, J. Savović, B. Tomazini, V. Veiga, S. Webb, J. Marshall +37 moresemanticscholar +1 more sourceAcute kidney injury in the critically ill: an updated review on pathophysiology and management
Intensive Care Medicine, 2021 Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient’s long-term prognosis.P. Pickkers, M. Darmon, E. Hoste, M. Joannidis, M. Legrand, M. Ostermann, J. Prowle, A. Schneider, M. Schetz +8 moresemanticscholar +1 more source
