Results 231 to 240 of about 6,755,416 (402)

Covid-19: Critically ill patients treated with arthritis drug tocilizumab show improved outcomes, researchers report [PDF]

, 2020
Jacqui Wise
openalex   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Physiotherapy approaches for pain control in patients who are critically ill. [PDF]

World J Crit Care Med
Ometto AC, Marcelino GB, Pereira GCN, Rodrigues FFP, Eid RAC, da Silva AA.   +5 more
europepmc   +1 more source

Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US.

JAMA Internal Medicine, 2020
Shruti Gupta, S. Hayek, Wei Wang, L. Chan, K. Mathews, M. Melamed, Samantha K. Brenner, A. Leonberg-Yoo, E. Schenck, Jared Radbel, J. Reiser, Anip Bansal, Anand Srivastava, Yan Zhou, A. Sutherland, Adam Green, Alexandre M. Shehata, Nitender Goyal, A. Vijayan, J. Velez, S. Shaefi, C. Parikh, Justin Arunthamakun, A. Athavale, A. Friedman, S. Short, Zoe A. Kibbelaar, Samah Abu Omar, A. Admon, J. Donnelly, H. Gershengorn, M. Hernán, M. Semler, D. Leaf   +33 more
semanticscholar   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Concept analysis of feeding intolerance in critically ill children

Huli yanjiu
ObjectiveTo analyze the definition and connotation of feeding intolerance in critically ill children,to provide a theoretical basis for research and clinical practice.MethodsLiterature on feeding intolerance in critically ill children was retrieved from ...
LI Yan, JU Minjie, FU Conghui, TANG Wenjuan, XU Tingting   +4 more
doaj  

Reconsidering vancomycin trough targets in critically-ill patients. [PDF]

Crit Care
Movahedan M, Lee C, Leung V.
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source