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Critical illness polyneuropathy
Current Opinion in Critical Care, 2002Critical illness polyneuropathy (CIP) is a syndrome that was first extensively described in the early 1980s, mainly in patients with failure to wean from mechanical ventilation. The syndrome is further characterized by limb muscle weakness, usually more pronounced distally than proximally, and is often accompanied by atrophy.
Walther N K A, van Mook +1 more
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Critical illness polyneuropathy
Current Opinion in Neurology, 2001Critical illness polyneuropathy is a self-limited acute axonal neuropathy that develops during treatment of severely ill patients and remits spontaneously once the critical condition is under control. Clinical manifestations include muscle weakness and atrophy, delayed weaning from the respirator, and prolongation of the mobilization phase.
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Critical Illness Neuromyopathy
Physical Medicine and Rehabilitation Clinics of North America, 2008Critical illness myopathy, neuropathy, and neuromyopathy are frequently encountered in the intensive care unit, particularly in the setting of sepsis and the systemic inflammatory response syndrome. A multidisciplinary approach is important to optimize management and minimize debility associated with these neuromuscular disorders.
Brent P, Goodman, Andrea J, Boon
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Critical Care Medicine, 2017
Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
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Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
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New England Journal of Medicine, 2014
Early in my intern year, I admitted an 80-year-old man with pneumonia to the intensive care unit (ICU). He had hypotension and was struggling to breathe, and my senior resident and I told his family that it was touch and go. Their response: Do everything. He had repaired cars for a living, and he was a tough guy, a fighter.
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Early in my intern year, I admitted an 80-year-old man with pneumonia to the intensive care unit (ICU). He had hypotension and was struggling to breathe, and my senior resident and I told his family that it was touch and go. Their response: Do everything. He had repaired cars for a living, and he was a tough guy, a fighter.
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Critically ill-Polyneuropathie
Fortschritte der Neurologie · Psychiatrie, 1997"Critically ill" polyneuropathy occurs in patients with artificial respiration. It is more frequent in men than in women. The most frequent underlying diseases, in the course of which CIP was found, were pneumonias, traumas and major surgery. In most cases sepsis and/or multiple organ dysfunction syndrome can be observed.
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Capnography During Critical Illness
Chest, 2016Capnography has made steady inroads in the ICU and is increasingly used for all patients who are mechanically ventilated. There is growing recognition that capnography is rich in information about lung and circulatory physiology and provides insight into many diseases and treatments.
Boulos S, Nassar, Gregory A, Schmidt
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Critical Illness Neuromuscular Syndromes
Critical Care Clinics, 2006Critical illness neuromyopathy (CINM) is the most common peripheral neuromuscular disorder encountered in the ICU. Bilateral diffuse weakness predominant in the proximal part of the limbs after improvement of the acute phase of the critical illness is highly suggestive of CINM.
Bernard, De Jonghe +3 more
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Current Rheumatology Reports, 2002
Acute myopathy is a common problem in intensive care units. Those at highest risk for developing critical illness myopathy are exposed to intravenous corticosteroids and paralytic agents during treatment of various illnesses. Diffuse weakness and failure to wean from mechanical ventilation are the most common clinical manifestations.
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Acute myopathy is a common problem in intensive care units. Those at highest risk for developing critical illness myopathy are exposed to intravenous corticosteroids and paralytic agents during treatment of various illnesses. Diffuse weakness and failure to wean from mechanical ventilation are the most common clinical manifestations.
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Micronutrients in Critical Illness
Critical Care Clinics, 1995Micronutrients play a key role in many of the metabolic processes that promote survival from critical illness. For vitamins, these processes include oxidative phosphorylation, which is altered in the patient with systemic inflammation, and protection against mediators, in particular oxidants. Trace elements are essential for direct antioxidant activity
R H, Demling, M A, DeBiasse
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