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Care for Critically Ill Patients With COVID-19.

Journal of the American Medical Association (JAMA), 2020
Initial reports suggest that COVID-19 is associated with severe disease that requires intensive care in approximately 5% of proven infections.1 Given how common the disease is becoming, as in prior major severe acute respiratory infection outbreaks—SARS (
S. Murthy, C. Gomersall, R. Fowler
semanticscholar   +1 more source

Exosomes in Critical Illness

Critical Care Medicine, 2017
Objective: Exosomes are small, cell-released vesicles (40–100 nm in size) with the potential to transfer proteins, lipids, small RNAs, messenger RNAs, or DNA between cells via interstitial fluids. Due to their role in tissue homeostasis, exosomes have emerged as a new type of therapeutic and diagnostic (theranostic) tool in the
TERRASINI, NORA, LIONETTI, Vincenzo
openaire   +3 more sources

The Liver in Critical Illness

Critical Care Clinics, 2016
Caring for critically ill patients with acute and/or chronic liver dysfunction poses a unique challenge. Proper resuscitation and early consideration for transfer to liver transplant centers have resulted in improved outcomes. Liver support devices and cellular models have not yet shown mortality benefit, but they hold promise in the critical care of ...
Damm, Tessa W, Kramer, David
openaire   +4 more sources

The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults.

Chest, 1991
The objective of this study was to refine the APACHE (Acute Physiology, Age, Chronic Health Evaluation) methodology in order to more accurately predict hospital mortality risk for critically ill hospitalized adults.
W. Knaus   +9 more
semanticscholar   +1 more source

Anemia in the critically ill

Critical Care Clinics, 2004
The anemia of critical illness is a distinct clinical entity with characteristics similar to that of chronic disease anemia. Several solutions to the processes of anemia, such as blunted erythropoietin production and erythropoietin response and abnormalities in iron metabolism have been developed.
Aryeh Shander, Aryeh Shander
openaire   +3 more sources

Diarrhoea in the Critically Ill

Intensive Care Medicine, 1986
“Diarrhoea” is derived from the Greek for a flowing trough. It is difficult to define precisely because of the wide variation in normal bowel habit, but definitions always include increased frequency and liquid consistency of the stool.
openaire   +3 more sources

Critical illness polyneuropathy

Current Treatment Options in Neurology, 2000
Critical illness polyneuropathy (CIP) is common among patients in intensive care units (ICUs). However, it is rarely diagnosed in patients in most ICUs, because of the lack of knowledge, difficulties in clinical assessment, and failure to perform electrophysiologic studies.
Charles F. Bolton, GB Young
openaire   +3 more sources

Critical Illness Polyneuropathy and Critical Illness Myopathy

2003
Neuromuscular disorders alone can account for up to 62% of the cases of ventilatory dependency in intensive care unit (ICU) patients with no other apparent causes of failure to wean, and they may be a contributing factor in up to 86% of these patients (Spitzer et al. 1992).
C. Serrano-Munuera, I. Illa
openaire   +2 more sources

Diarrhoea in the critically ill

Current Opinion in Critical Care, 2015
To summarize existing evidence on definition, epidemiology, mechanisms, risk factors, consequences, outcome and management of diarrhoea in the critically ill.In health, diarrhoea is defined as the passage of three or more loose or liquid stools per day.
Reintam Blaser, A.   +2 more
openaire   +4 more sources

Laparoscopy in the critically ill

Surgical Endoscopy, 1997
Laparoscopy was evaluated in critically ill patients with suspected acute cholecystitis, mesenteric ischemia, or gastrointestinal perforation. We studied laparoscopy to assess its utility, accuracy, and effect on cardiopulmonary stability.Twenty-six surgical ICU patients with possible abdominal sepsis underwent laparoscopy.
K. L. Crowell, R. Orlando
openaire   +3 more sources

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