Results 61 to 70 of about 273,867 (249)

Efficacies of Colistin–Carbapenem versus Colistin–Tigecycline in Critically Ill Patients with CR-GNB-Associated Pneumonia: A Multicenter Observational Study [PDF]

, 2021
Sheng‐Huei Wang, Kuang‐Yao Yang, Chau‐Chyun Sheu, Wei-Cheng Chen, Ming-Cheng Chan, Jia‐Yih Feng, Chia-Min Chen, Biing‐Ru Wu, Zhe-Rong Zheng, Yu‐Ching Chou, Chung‐Kan Peng   +10 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Successful treatment of a resistant invasive disseminated Fusarium infection in an immunocompetent patient

Medical Mycology Case Reports
Fusariosis is a severe fungal infection associated with high mortality rates and an increasing incidence. However, its treatment remains challenging due to the frequent resistance of Fusarium species to conventional antifungal therapies.
Frantzeska Frantzeskaki, Nikolas Stratopoulos, Sandra Elise van der Griend, Ioannis Renieris, Kostantinos Thomas, Iraklis Tsagkaris   +5 more
doaj   +1 more source

Community-Onset Bacterial Coinfection in Children Critically Ill With Severe Acute Respiratory Syndrome Coronavirus 2 Infection [PDF]

, 2023
Kristin Moffitt, Mari Nakamura, Cameron C. Young, Margaret M. Newhams, Natasha Halasa, J Reed, Julie Fitzgerald, Philip C. Spinella, Vijaya L Soma, Tracie C. Walker, Laura L. Loftis, Aline B. Maddux, Michele Kong, Courtney M. Rowan, Charlotte V. Hobbs, Jennifer E. Schuster, Becky J. Riggs, Gwenn E. McLaughlin, Kelly N. Michelson, Mark W. Hall, Christopher J. Babbitt, Natalie Z. Cvijanovich, Matt S. Zinter, Mia Maamari, Adam J. Schwarz, Aalok R. Singh, Heidi R. Flori, Shira J. Gertz, Mary Allen Staat, John S. Giuliano, Saul Hymes, Katharine N. Clouser, John K. McGuire, Christopher L. Carroll, Neal J. Thomas, Emily R. Levy, Adrienne G. Randolph   +36 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Nebulized tranexamic acid for recurring hemoptysis in critically ill patients: case series [PDF]

, 2020
Fatimah Alabdrabalnabi, Mohammed Alshahrani, Nadia Ismail   +2 more
openalex   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Covid-19: Critically ill patients treated with arthritis drug tocilizumab show improved outcomes, researchers report [PDF]

, 2020
Jacqui Wise
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Statins-More Than Just Plaque Stabilisation

Indian Journal of Anaesthesia, 2008
Hydroxymethylglutaryl-CoA reductase inhibitors, better known as statins have come a long way in the recent years, not just in perioperative cardiac protection but also as potential agents for the critically ill patient in intensive care.
Ashish K Khanna, Satinder Gombar
doaj