Results 151 to 160 of about 1,231,981 (407)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

THU331 Glycemic Variability In Critically Ill Sepsis Patients Comorbid With COVID-19: Relative Impact Of Diabetes And/Or Obesity [PDF]

, 2023
Janevi Rebernigg, Karla Herrera Baez, Nicole Torres Rivera, Berkis Contreras, Sage Yenari, Karen Hamad, Wilhelmine Wiese‐Rometsch, Vida Farhangi   +7 more
openalex   +1 more source

Hyponatremia in critically ill patients

Indian Journal of Critical Care Medicine, 2014
Hyponatremia is a common electrolyte disturbance in critically ill hence understanding its implications is important.This study was carried out to ascertain frequency, predisposing conditions and outcome in critically ill patients with hyponatremia on intensive care unit (ICU) admission.This was an observational, prospective study of a series of ICU ...
Padhi, Rajesh, Panda, Baikuntha Nath, Jagati, Snehalata, Patra, Subhas Chandra   +3 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prevalence and Seven-day Observation of Critically Ill Patients in Cipto Mangunkusumo Hospital, Jakarta: a Preliminary Study [PDF]

, 2013
Current medical record system in Cipto Mangunkusumo Hospital (RSCM) does not allow up-to-dateidentification for patients with critical condition. As an effort on improving the rapid response of themedical team, this study aims to determine the number of ...
Anggreni, M. (Meliani), Firdaus, R. (Riyadh), Supit, T. (Tommy)   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effect of Adding Insulin Glargine on Glycemic Control in Critically Ill Patients Admitted to Intensive Care Units: A Prospective Randomized Controlled Study

Diabetes, Metabolic Syndrome and Obesity, 2020
Nader D Nader,1 Hadi Hamishehkar,2 Abdolreza Naghizadeh,3 Kamran Shadvar,3 Afshin Iranpour,4 Sarvin Sanaie,5 Francis Chang,1 Ata Mahmoodpoor3 1State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA ...
Nader ND, Hamishehkar H, Naghizadeh A, Shadvar K, Iranpour A, Sanaie S, Chang F, Mahmoodpoor A   +7 more
doaj  

The Relationship Between Undernutrition and Mortality in Critically ill Patients : A Literature Review

, 2023
D.K. Rose, Arina Setyaningtyas, Nur Aisiyah Widjaja, Bambang Pudjo Semedi   +3 more
openalex   +2 more sources

Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries.

Journal of the American Medical Association (JAMA), 2021
V. Russotto, S. Myatra, J. Laffey, E. Tassistro, L. Antolini, P. Bauer, J. Lascarrou, Konstanty Szułdrzyński, L. Camporota, P. Pelosi, M. Sorbello, A. Higgs, R. Greif, C. Putensen, Christina Agvald-Öhman, A. Chalkias, K. Bokums, D. Brewster, E. Rossi, R. Fumagalli, A. Pesenti, G. Foti, G. Bellani   +22 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source