Results 161 to 170 of about 1,231,981 (407)

Measurement of endotoxin activity in critically ill patients using whole blood neutrophil dependent chemiluminescence [PDF]

, 2002
John C. Marshall, Paul M. Walker, Debra Foster, David Harris, Melanie B. Ribeiro, Jeff Paice, Alexander D. Romaschin, Anastasia Derzko   +7 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

A study to evaluate the efficacy of intravenous Magnesium Sulphate administration on lactate clearance in critically ill patients

Ibom Medical Journal
Background: Magnesium (Mg) is crucial for normal mitochondrial function in human body. It functions as an important cofactor for numerous biological reactions involving ATP-generating enzymes such as mitochondrial ATP synthase and Na+/K+ ATPase ...
Rani A, Ghai A, Puhal S, Bansal P, Varghese V   +4 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Resting energy expenditure in critically ill patients: Evaluation methods and clinical applications [PDF]

, 2016
Ana Cláudia Soncini Sanches, Cassiana Regina de Góes, Marina Nogueira Berbel Bufarah, André Luís Balbi, Daniela Ponce   +4 more
openalex   +1 more source

Renin in critically ill patients

Annals of Intensive Care
AbstractThe renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain hemodynamic and fluid homeostasis. However, most research until now on RAS primarily focuses on its relationship with hypertension and its role in critically ill hypotensive populations is not well understood.
Yuki Kotani, Mark Chappell, Giovanni Landoni, Alexander Zarbock, Rinaldo Bellomo, Ashish K. Khanna   +5 more
openaire   +6 more sources

Pediatric Resuscitation: Evaluation of a Clinical Curriculum [PDF]

, 2003
Objective: To assess the impact of a 6-hour pediatric resuscitation curriculum on the comfort levels of resident physicians’ evaluation and treatment of critically ill pediatric patients. Methods: An evaluation instrument assessed resident comfort levels,
Brancati , DO, David S., Dobson , MD, Joseph V., Nagel , PhD, Rollin   +2 more
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Role of Rifaximin in the Prognosis of Critically Ill Patients with Liver Cirrhosis

Antibiotics
Background/Objectives: Critically ill patients with liver cirrhosis impose a substantial health burden on the world. Rifaximin is a potential treatment option for such patients.
Zhaohui Bai, Congcong Li, Yongjie Lai, Xiaojuan Hu, Luwen Shi, Xiaodong Guan, Yang Xu   +6 more
doaj   +1 more source

Covid-19: Critically ill patients treated with arthritis drug tocilizumab show improved outcomes, researchers report [PDF]

, 2020
Jacqui Wise
openalex   +1 more source