Results 191 to 200 of about 1,231,981 (407)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Efficiency of dosing software using Bayesian forecasting in achieving target antibiotic exposures in critically ill patients, a prospective cohort study

, 2023
Ming G. Chai, Jason A. Roberts, Christina F. Kelly, Jacobus Ungerer, Brett McWhinney, Jeffrey Lipman, András Farkas, Menino Osbert Cotta   +7 more
openalex   +1 more source

Intensive insulin therapy in critically ill patients.

New England Journal of Medicine, 2001
G. V. Berghe, P. Wouters, F. Weekers, C. Verwaest, F. Bruyninckx, M. Schetz, D. Vlasselaers, P. Ferdinande, P. Lauwers, R. Bouillon   +9 more
semanticscholar   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Effect of remimazolam besylate on elderly patients with mechanical ventilation: a single-center randomized controlled study

BMC Anesthesiology
Objective To compare the clinical prognosis and offline strategy differences between remimazolam besylate and propofol for sedation in elderly patients undergoing mechanical ventilation.
Yihui Li, Yamin Yuan, Jinquan Zhou, Li Ma   +3 more
doaj   +1 more source

Research on the Construction and Application of Communication Protocols for the Transfer of Critically Ill Cancer Patients in ICU under the Background of MEWS Early Warning Score [PDF]

Yanyu Chen, Qiongyao Guan, Wenting Zhang, Xiaohua Ren, Xiangping Ma, S. S. Yang, Yuan‐Han Yang   +6 more
openalex   +1 more source

Blood return at the end of renal replacement therapy provided clues on fluid responsiveness in critically ill patients with shock [PDF]

, 2022
Daozheng Huang, Jie Ma, Shouhong Wang, Tiehe Qin, Feier Song, Tieying Hou, Huan Ma   +6 more
openalex   +1 more source

Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis

Thrombosis Research, 2020
F. Klok, M. Kruip, N. Meer, M. Arbous, D. Gommers, Krishna Kant, F. Kaptein, J. Paassen, M. Stals, M. Huisman, H. Endeman   +10 more
semanticscholar   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source