Association of IRGM gene mutations with inflammatory bowel disease in the Indian population. [PDF]
PLoS ONE, 2014 Mutations in the IRGM gene have been associated with Crohn's disease in several populations but have not been explored in Indian patients with this disease. This study examined the association of IRGM mutations with ulcerative colitis and Crohn's disease
Kirankumar Baskaran +2 more
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Medicine, 2003 Abstract Understanding the aetiology and pathogenesis of Crohn's disease remains a challenge, but it is clearly an interaction between the environment and a genetically susceptible individual. Multiple genes are being described, each contributing a small degree of susceptibility or protection, but the functional consequences of gene mutations are not ...
Gunnar Järnerot, Rune Sjödahl
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Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
, 2002 Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian +5 more
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Extraintestinal Crohn's disease (metastatic Crohn's disease)
Przegląd Dermatologiczny, 2014 Crohn's disease (CD) is an inflammatory bowel disorder that may involve any segment of the gastrointestinal tract from the oral cavity to the anus. CD belongs to the group of nonspecific inflammatory bowel diseases of unknown etiology.
Michał Rożalski
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Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]
, 2007 The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Altorjay, István +3 more
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Radiological sacroiliitis, a hallmark of spondylitis, is linked with CARD15 gene polymorphisms in patients with Crohn's disease [PDF]
, 2004 Background: Sacroiliitis is a common extraintestinal manifestation of Crohn's disease but its association with the HLA-B27 phenotype is less evident. Polymorphisms in the CARD15 gene have been linked to higher susceptibility for Crohn's disease.
Coucke, Paul +10 more
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Sweet's syndrome in a patient with Crohn's disease: a case report
Journal of Medical Case Reports, 2008 Background Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, has been associated with malignancy, autoimmune disease and collagen vascular disease. The association of Crohn's disease and Sweet's syndrome is rare.
Mustafa Nadia M, Lavizzo Mark
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Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
, 2006 The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
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The Lancet, 2012 Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. Genome wide association studies identified susceptibility loci that--triggered by environmental factors--result in a disturbed innate (ie, disturbed intestinal barrier, Paneth ...
William J. Sandborn, Daniel C. Baumgart
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Recent trends in the epidemiology of inflammatory bowel diseases: up or down? [PDF]
, 2006 Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s.
Lakatos, Péter László
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