Results 31 to 40 of about 10,538,494 (333)

Clinical presentation of Crohn's disease. Association between familial disease, smoking, disease phenotype, extraintestinal manifestations and need for surgery

, 2005
Background/Aims: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in Crohn's disease (CD). It was also suggested that familial inflammatory bowel disease (IBD) is a homogenous subgroup, phenotypically ...
Gasztonyi, Beáta, Kovács, Attila, Figler, Mária, Szalay, Ferenc, Cseh, J., Mikó, Éva, Horváth, Gábor, Szekeres Barthó, J., Papp, János, Lakatos, Péter László, Molnár, Tamás, Kovács, Ágota, Lakatos, Péter, Hunyady, Béla, Tulassay, Zsolt, Kisbenedek, A. G., Lakatos, László   +16 more
core   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

The association between Crohn's disease activity, serum 25(oh)- vitamin d status, the disease-associated environmental risk factors and the variability of Crohn's disease phenotype in the Western Cape population, South Africa [PDF]

, 2014
Philosophiae Doctor - PhDBackground: A subtype of inflammatory bowel disease, Crohn' s disease is thought to represent a complex interaction between environmental factors, a defective immune system, the gastrointestinal microbiome and genetic ...
Basson, Abigail Raffner
core   +1 more source

Multicentric Cutaneous Crohn's Disease: A Case Report and Review of Literature

Canadian Journal of Gastroenterology, 1990
A patient presented with skin lesions at sites not contiguous with Crohn's disease of the bowel and with specific histological features of Crohn's disease occurring two weeks from the onset of bowel symptoms.
Robert Prokopetz, J Barrie Ross, Peter Smith, Joseph J Sidorov   +3 more
doaj   +1 more source

Timing of ileocolonic anastomosis in ileocecal resection in Crohn's disease [PDF]

, 2023
openABSTRACT Background - Crohn's disease (CD) is a chronic inflammatory disorder affecting the gastrointestinal tract with no current curative treatment. Despite significant improvements in medical treatments, surgery is still necessary in most cases,
BOSCARO, VITTORIA
core  

Progress and Clinical Applications of Crohn’s Disease Exclusion Diet in Crohn’s Disease

Gut and Liver
Crohn’s disease is a chronic intestinal inflammatory disorder of unknown etiology. Although the pharmacotherapies for Crohn’s disease are constantly updating, nutritional support and adjuvant therapies have recently gained more attention.
Duo Xu, Ziheng Peng, Yong Li, Qian Hou, Yu Peng, Xiaowei Liu   +5 more
doaj   +1 more source

Serological markers for prediction of response to anti-tumor necrosis factor treatment in Crohn's disease [PDF]

, 2002
peer reviewedOBJECTIVES: The use of monoclonal anti-tumor necrosis factor (TNF) antibodies (infliximab, Remicade) is a new therapeutic approach for severe refractory luminal or fistulizing, Crohn's disease (CD).
FIASSE, R, POULAIN, D, Rutgeerts, P., Fiasse, René, Rutgeerts, Paul, Esters, N., Reynaert, Hendrik, Reynaert, H., Poulain, Daniel, Poulain, D., Esters, Nele, Van Gossum, A., Belaiche, Jacques, Van Gossum, André, Pelckmans, Paul, PELCKMANS, P, Bossuyt, Xavier, Pescatore, Pierre, PESCATORE, P, Joossens, Sofie, Louis, E., VAN GOSSUM, A, ESTERS, N, RUTGEERTS, P, Noman, Maja, Vermeire, S., Noman, M., De Vos, M., Bela\uefche, J., De Vos, M, JOOSSENS, S, NOMAN, M, LOUIS, E, Belgian Group of Infliximab Expanded Access Program in Crohn's Disease, BOSSUYT, X, Louis, Edouard, Bossuyt, X., Fiasse, R., De Vos, Martine, Pescatore, Paul, Pelckmans, P., VERMEIRE, S, BELAICHE, J, REYNAERT, H, Joossens, S., Pescatore, P., Vermeire, Séverine   +46 more
core   +1 more source

Pulmonary Extraintestinal Manifestation of Crohn’s Disease Treated Successfully with Adalimumab

The Korean Journal of Gastroenterology, 2018
Pulmonary extraintestinal manifestation is rare in Crohn’s disease and has been reported in only a few cases. Despite the presence of pulmonary abnormalities in a significant proportion of patients with inflammatory bowel disease, there are only few case
Dongyeol Shin, Byung Kyu Park, Jeonghun Seo, Sun Young Won, Mi Kyoung Lee, Yong Kook Hong, Yong Suk Cho   +6 more
doaj   +1 more source

Metastatic Crohn’s disease despite infliximab therapy [PDF]

Anais Brasileiros de Dermatologia, 2017
Metastatic Crohn’s disease is a rare extraintestinal manifestation of Crohn’s disease. It is characterized by polymorphic skin lesions formed by non-caseating granulomas located on anatomical sites distant from the gastrointestinal tract.
Sara Campos, Inês Coutinho, José Carlos Cardoso, Francisco Portela   +3 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source