Results 31 to 40 of about 10,512,482 (403)

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Nature Genetics, 2008
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data from three studies on Crohn's disease (a total of 3,230 cases and 4,829 controls) and carried out
J. Barrett, S. Hansoul, Dan L. Nicolae, Judy H. Cho, R. Duerr, J. Rioux, J. Rioux, S. Brant, M. Silverberg, K. Taylor, M. Barmada, A. Bitton, T. Dassopoulos, L. Datta, Todd Green, A. Griffiths, E. Kistner, M. Murtha, M. Regueiro, J. Rotter, L. Schumm, A. Steinhart, S. Targan, R. Xavier, C. Libioulle, C. Sandor, M. Lathrop, J. Belaiche, O. Dewit, I. Gut, S. Heath, D. Laukens, M. Mni, P. Rutgeerts, A. Gossum, D. Zélénika, D. Franchimont, J. Hugot, M. Vos, S. Vermeire, E. Louis, L. Cardon, C. Anderson, H. Drummond, E. Nimmo, T. Ahmad, N. Prescott, Clive M. Onnie, S. Fisher, J. Marchini, J. Ghori, S. Bumpstead, R. Gwilliam, M. Tremelling, P. Deloukas, J. Mansfield, D. Jewell, J. Satsangi, C. Mathew, M. Parkes, M. Georges, M. J. Daly, M. J. Daly   +62 more
semanticscholar   +1 more source

Crohn's disease

The Lancet, 2012
Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. Genome wide association studies identified susceptibility loci that--triggered by environmental factors--result in a disturbed innate (ie, disturbed intestinal barrier, Paneth ...
Baumgart, Daniel C, Sandborn, William J
openaire   +2 more sources

Recent trends in the epidemiology of inflammatory bowel diseases: up or down? [PDF]

, 2006
Inflammatory bowel disease (IBD) is traditionally considered to be common in the Western world, and its incidence has sharply increased since the early 1950s.
Lakatos, Péter László
core   +1 more source

FOCAL ENHANCED GASTRITIS AND MACROPHAGE MICROAGGREGATES IN THE GASTRIC MUCOSA: potential role in the differential diagnosis between Crohn’s disease and ulcerative colitis

Arquivos de Gastroenterologia, 2014
Context and Objectives Focally enhanced gastritis and macrophage microaggregates are found in the upper gastrointestinal involvement of Crohn’s disease, and may reflect an underlying defective innate immunity.
Marcia Henriques de MAGALHÃES-COSTA, Beatriz Ribeiro dos REIS, Vera Lúcia Antunes CHAGAS, Tiago NUNES, Heitor Siffert Pereira de SOUZA, Cyrla ZALTMAN   +5 more
doaj   +1 more source

EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version). [PDF]

, 2016
▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting.
Calabrese, E., Dietrich, C. F., Dirks, K., Gilja, O. H., Hausken, T., Higginson, A., Hollerweger, A., Maaser, C., Maconi, G., Nuernberg, D., Nylund, K., Pallotta, Nadia, Ripolles, T., Romanini, L., Saftoiu, A., Serra, C., Sporea, I.   +16 more
core   +3 more sources

Radiologic images of complications of Crohn's disease

International Journal of Gastrointestinal Intervention, 2023
Crohn's disease is a chronic inflammatory disease that may occur in the alimentary tract and has various clinical courses. It is characterized by several complications, including bowel strictures, bowel obstruction, fistulas, abscesses, and ...
Sungjin Yoon, So Hyun Park, Jun Seong Kim   +2 more
doaj   +1 more source

Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian, Glas, J., Herbinger, K. H., Hoelscher, Michael, Török, H.-P., Vilsmaier, F.   +5 more
core   +1 more source

Diagnosis and outcome of oesophageal Crohn's disease [PDF]

, 2019
BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
Beaton, D, Chaparro, M, Ellul, P, Katsanos, K, Oliveira, AM, et al., Rodrigues, R, Savarino, E, Sladek, M, Teich, N, van der Woude, J, Vavricka, R, Wei, J   +11 more
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Crohn disease

Autopsy and Case Reports, 2015
Aretaeus of Cappadocia (1st century CE) described a young man with chronic and recurring abdominal distress possibly representing the first recorded instance of Crohn disease (CD).1-3 More evidence that this disease was extant for many years comes from the description of the 10th century English king, Alfred “the great,” who suffered for many years ...
Stephen A. Geller, Fernando Peixoto Ferraz de Campos   +1 more
openaire   +3 more sources

The Prevalence of Headache in Crohn’s Disease: Single-Center Experience

Gastroenterology Research and Practice, 2016
Objectives. This study is aimed at studying the prevalence and characteristics of different types of headaches in patients with Crohn’s disease. Materials and Methods.
Ulker Anadol Kelleci, Turan Calhan, Abdurrahman Sahin, Resul Kahraman, Kamil Ozdil, Haci Mehmet Sokmen, Destina Yalcin   +6 more
doaj   +1 more source