Results 11 to 20 of about 10,538,494 (333)

ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment. [PDF]

Journal of Crohn's & Colitis, 2019
This article is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease.
M. Adamina, S. Bonovas, T. Raine, A. Spinelli, J. Warusavitarne, A. Armuzzi, O. Bachmann, P. Bager, L. Biancone, B. Bokemeyer, P. Bossuyt, J. Burisch, P. Collins, G. Doherty, A. El‐Hussuna, P. Ellul, G. Fiorino, C. Frei-Lanter, F. Furfaro, C. Gingert, P. Gionchetti, J. Gisbert, F. Gomollón, Marien González Lorenzo, H. Gordon, T. Hlavatý, P. Juillerat, K. Katsanos, U. Kopylov, E. Krustiņš, T. Kucharzik, T. Lytras, C. Maaser, F. Magro, J. K. Marshall, P. Myrelid, Gianluca Pellino, I. Rosa, J. Sabino, E. Savarino, L. Stassen, J. Torres, Mathieu Uzzan, S. Vavricka, B. Verstockt, O. Zmora   +45 more
semanticscholar   +2 more sources

Crohn's disease [PDF]

The Lancet, 2012
Crohn's disease is a relapsing systemic inflammatory disease, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. Genome wide association studies identified susceptibility loci that--triggered by environmental factors--result in a disturbed innate (ie, disturbed intestinal barrier, Paneth ...
Baumgart, Daniel C, Sandborn, William J
core   +4 more sources

ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment.

Journal of Crohn's & Colitis
This article is the second in a series of two publications on the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease.
M. Adamina, Silvia Minozzi, J. Warusavitarne, Christianne J Buskens, María Chaparro, B. Verstockt, U. Kopylov, M. Agrawal, M. Allocca, Raja Atreya, R. Battat, Dominik Bettenworth, G. Bislenghi, Steven Ross Brown, J. Burisch, M. Casanova, Wladyslawa Czuber-Dochan, J. de Groof, A. El‐Hussuna, P. Ellul, C. Fidalgo, G. Fiorino, J. Gisbert, J. Sabino, J. Hanžel, S. Holubar, M. Iacucci, N. Iqbal, C. Kapizioni, K. Karmiris, Taku Kobayashi, Paulo Gustavo Kotze, G. Luglio, C. Maaser, G. Moran, N. Noor, K. Papamichail, G. Peros, C. Reenaers, G. Sica, R. Sigall-Boneh, S. Vavricka, H. Yanai, T. Raine, H. Gordon, P. Myrelid   +45 more
semanticscholar   +3 more sources

Association of IRGM gene mutations with inflammatory bowel disease in the Indian population. [PDF]

PLoS ONE, 2014
Mutations in the IRGM gene have been associated with Crohn's disease in several populations but have not been explored in Indian patients with this disease. This study examined the association of IRGM mutations with ulcerative colitis and Crohn's disease
Kirankumar Baskaran, Srinivasan Pugazhendhi, Balakrishnan S Ramakrishna   +2 more
doaj   +1 more source

Extraintestinal Crohn's disease (metastatic Crohn's disease)

Przegląd Dermatologiczny, 2014
Crohn's disease (CD) is an inflammatory bowel disorder that may involve any segment of the gastrointestinal tract from the oral cavity to the anus. CD belongs to the group of nonspecific inflammatory bowel diseases of unknown etiology.
Michał Rożalski
doaj   +1 more source

The treatment-naive microbiome in new-onset Crohn's disease.

Cell Host and Microbe, 2014
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), are genetically linked to host pathways that implicate an underlying role for aberrant immune responses to intestinal microbiota.
D. Gevers, S. Kugathasan, L. Denson, Y. Vázquez-Baeza, William W. Van Treuren, Boyu Ren, Emma H. Schwager, D. Knights, S. Song, Moran Yassour, X. Morgan, A. Kostic, Chengwei Luo, Antonio Gonzalez, Daniel McDonald, Y. Haberman, T. Walters, S. Baker, J. Rosh, Michael C. Stephens, M. Heyman, J. Markowitz, R. Baldassano, A. Griffiths, F. Sylvester, D. Mack, Sandra C. Kim, W. Crandall, J. Hyams, C. Huttenhower, R. Knight, R. Xavier   +31 more
semanticscholar   +1 more source

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Nature Genetics, 2008
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data from three studies on Crohn's disease (a total of 3,230 cases and 4,829 controls) and carried out
J. Barrett, S. Hansoul, Dan L. Nicolae, Judy H. Cho, R. Duerr, J. Rioux, J. Rioux, S. Brant, M. Silverberg, K. Taylor, M. Barmada, A. Bitton, T. Dassopoulos, L. Datta, Todd Green, A. Griffiths, E. Kistner, M. Murtha, M. Regueiro, J. Rotter, L. Schumm, A. Steinhart, S. Targan, R. Xavier, C. Libioulle, C. Sandor, M. Lathrop, J. Belaiche, O. Dewit, I. Gut, S. Heath, D. Laukens, M. Mni, P. Rutgeerts, A. Gossum, D. Zélénika, D. Franchimont, J. Hugot, M. Vos, S. Vermeire, E. Louis, L. Cardon, C. Anderson, H. Drummond, E. Nimmo, T. Ahmad, N. Prescott, Clive M. Onnie, S. Fisher, J. Marchini, J. Ghori, S. Bumpstead, R. Gwilliam, M. Tremelling, P. Deloukas, J. Mansfield, D. Jewell, J. Satsangi, C. Mathew, M. Parkes, M. Georges, M. Daly, M. Daly   +62 more
semanticscholar   +1 more source

Sweet's syndrome in a patient with Crohn's disease: a case report

Journal of Medical Case Reports, 2008
Background Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, has been associated with malignancy, autoimmune disease and collagen vascular disease. The association of Crohn's disease and Sweet's syndrome is rare.
Mustafa Nadia M, Lavizzo Mark
doaj   +1 more source

Meta-Analysis Increases to 71 the Tally of Confirmed Crohn’s Disease Susceptibility Loci

Nature Genetics, 2010
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the top association signals in 15,694 cases, 14,026 controls and 414 parent ...
A. Franke, D. McGovern, J. Barrett, Kai Wang, Graham L. Radford-Smith, T. Ahmad, C. Lees, Tobias Balschun, James Lee, R. Roberts, C. Anderson, J. Bis, S. Bumpstead, D. Ellinghaus, Eleonora A. M. Festen, M. Georges, Todd Green, T. Haritunians, L. Jostins, A. Latiano, C. Mathew, G. Montgomery, N. Prescott, S. Raychaudhuri, Jerome I. Rotter, P. Schumm, Y. Sharma, L. Simms, K. Taylor, David C. Whiteman, C. Wijmenga, R. Baldassano, M. Barclay, Theodore M. Bayless, S. Brand, Carsten Büning, Albert Cohen, J. Colombel, M. Cottone, L. Stronati, T. Denson, M. Vos, R. D’Inca, M. Dubinsky, C. Edwards, T. Florin, D. Franchimont, R. Gearry, J. Glas, A. Gossum, S. Guthery, J. Halfvarson, H W Verspaget, J. Hugot, Amir S Karban, D. Laukens, I. Lawrance, M. Lémann, A. Levine, C. Libioulle, Edouard Louis, C. Mowat, William G. Newman, J. Panés, A. Phillips, D. Proctor, M. Regueiro, Richard Russell, P. Rutgeerts, J. Sanderson, M. Sans, F. Seibold, A. Steinhart, P. Stokkers, L. Torkvist, Gerd A. Kullak-Ublick, David C. Wilson, T. Walters, S. Targan, S. Brant, J. Rioux, M. D’Amato, R. Weersma, S. Kugathasan, A. Griffiths, J. Mansfield, S. Vermeire, R. Duerr, M. Silverberg, J. Satsangi, S. Schreiber, Judy H. Cho, V. Annese, H. Hakonarson, M. Daly, M. Parkes   +95 more
semanticscholar   +1 more source

Common NOD2/CARD15 variants are not associated with susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian patients [PDF]

, 2007
Background: Epidemiological observations suggest that cancer arises from chronically inflamed tissues. Inflammatory bowel disease (IBD) is a typical example as patients with longstanding IBD are at an increased risk for developing colorectal cancer (CRC)
Zinober Kerstin, Kerstin Zinober, Gemela, Orsolya, Veres, Gábor, Peter Ferenci, Fischer, Simon, Orsolya Gemela, Papp, János, Janos Papp, Ferenci Peter, Peter Fuszek, Gemela Orsolya, Szalay Ferenc, Erika Hitre, Osztovits, János, Fischer Simon, Szalay, Ferenc, Fuszek, Péter, Ferenc Szalay, Veres Gabor, Janos Osztovits, Laszlo Lakatos, Zinober, Kerstin, Hitre, Erika, Osztovits Janos, Peter Laszlo Lakatos, Lakatos, Péter László, Hitre Erika, Lakatos Laszlo, Papp Janos, Simon Fischer, Lakatos Peter, Ferenci, Péter, Lakatos, László, Fuszek Peter, Gabor Veres   +35 more
core   +1 more source