Results 41 to 50 of about 10,538,494 (333)

Two for One: Coexisting Ulcerative Colitis and Crohn’s Disease

open access: yesCanadian Journal of Gastroenterology, 2002
Three cases of coexisting ulcerative colitis and Crohn’s disease are presented. In the first case, the patient had a long-standing history of ulcerative proctitis before developing Crohn’s colitis.
Grant I Chen   +2 more
doaj   +1 more source

Reactive angioendotheliomatosis of the intestine in Crohn’s disease: A second case report with 10-year follow up

open access: yesHuman Pathology: Case Reports, 2015
Reactive angioendotheliomatosis (RAE) is a rare cutaneous vascular disorder, usually associated with systemic diseases. RAE has previously been described only in the skin, with the single exception of one case involving the intestine in a patient with ...
Hwajeong Lee, MD   +1 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

Adenocarcinoma arising from chronic perianal crohn's disease: a case report

open access: yesThe Pan African Medical Journal, 2015
Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas.
Hanane Massit   +5 more
doaj   +1 more source

Telocytes in Crohn's disease [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2013
AbstractCrohn's disease (CD) is a relapsing chronic inflammatory disorder that may involve all the gastrointestinal tract with a prevalence of terminal ileum. Intestinal lesions have a characteristic discontinuous and segmental distribution and may affect all layers of the gut wall.
A. F. Milia   +7 more
openaire   +3 more sources

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min   +6 more
wiley   +1 more source

Atypical Perinuclear Antineutrophil Cytoplasmic Antibodies in Patients with Crohn’s Disease

open access: yesCanadian Journal of Gastroenterology, 1997
Atypical perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) occur in most patients with ulcerative colitis but only in a minority of those with Crohn's disease ...
Hugh J Freeman
doaj   +1 more source

Progressive Primary Appendiceal Crohn’s Disease in a 21-Year-old Female

open access: yesCase Reports in Gastroenterology, 2020
Crohn’s disease is an inflammatory bowel disorder that can affect any portion of the gastrointestinal tract, most commonly the terminal ileum near the ileocecal valve.
Cullen Roberts   +3 more
doaj   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

Role of MR enterography in acute and chronic stages of Crohn's disease

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2018
Background: Crohn's disease (CD) is an autoimmune disease affecting young, adult with relapsing course. MRI is now considered a safe alternative for, diagnosing complication of Crohn s disease.
Rabab Yasin   +2 more
doaj   +1 more source

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