Results 171 to 180 of about 162,990 (305)

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Reasoning behind discrepancies in periodontal diagnosis and classification: A mixed‐methods analysis

Journal of Periodontology, EarlyView.
Abstract Background While discrepancies in periodontal diagnosis and classification among dental providers with various educational backgrounds have been reported when the 2017 Classification of Periodontal Conditions was applied, the cognitive reasoning processes underlying these discrepancies remain underexplored.
Seok‐Mo Heo, Thomas W. Oates, Se‐Lim Oh   +2 more
wiley   +1 more source

Health Technology Assessment of Infliximab: A Rapid Review of Type 2 Studies

مجله دانشکده پزشکی اصفهان, 2012
Background: Infliximab has been used for treatment of patients with Crohn's disease whose symptoms or developed fistula could not be eliminated by standard treatments.
Mohamadreza Mobinizadeh, Alireza Oliyaeemanesh, Sheila Doaee, Mina Nejati, Parisa Aboee, Mahdi Azadbakht, Mahboubeh Valadkhani6   +6 more
doaj  

Immunological and periodontal benefits of prebiotic polydextrose in rats with induced periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Prebiotic therapy is a promising approach for managing periodontitis due to its potential benefits in modulating the microbiome and the immune response. This study aimed to evaluate the effects of the prebiotic (PREB) polydextrose (PDX) on the development of experimental periodontitis (EP) in rats.
Raquel de S. F Nassar, Marcella C. Ribeiro, Ana Carolina P. Hernandes, Laura Z. Gianduzzo, Vanessa de P. S. Pereira, Sérgio L. S. Salvador, Edilson Ervolino, Débora S. F. Sávio, Michel R. Messora, Flávia A. C. Furlaneto   +9 more
wiley   +1 more source

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The increasing incidence of inflammatory bowel disease (IBD) in paediatric populations underscores the importance of effective management strategies. Anti–tumor necrosis factor (anti‐TNF) agents, such as infliximab (IFX) and adalimumab (ADL), are key treatments for inducing and maintaining remission in IBD, but many patients ...
Karlotta Pauline Hubert, Sebastian Stricker, Jan De Laffolie   +2 more
wiley   +1 more source

Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Adalimumab is commonly used to induce and maintain remission in pediatric Crohn's disease (CD). However, data on the efficacy and safety of high‐dose adalimumab in this population are limited. This study aimed to evaluate the therapeutic effectiveness and safety of weekly high‐dose adalimumab (80 mg) in pediatric CD patients ...
Eyal Cohen‐Sela, Anat Yerushalmy‐Feler, Firas Rinawi, Esther Orlanski‐Meyer, Raouf Nassar, Ramit Magen‐Rimon, Yael Weintraub, Raanan Shamir, Dror S. Shouval, Manar Matar   +9 more
wiley   +1 more source

The prognostic role of magnetic resonance enterography at diagnosis in paediatric isolated ileocaecal Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We aimed at identifying magnetic resonance enterography (MRE) predictors of surgical intervention and anti‐tumor necrosis factor alpha (TNF‐α) initiation in a paediatric cohort of patients newly diagnosed with isolated ileocaecal (L1) Crohn's disease (CD).
Saverio Pochesci, Luca Scarallo, Federico Rubera, Arianna Pranzetti, Marco Di Maurizio, Massimo Basile, Paolo Emilio Orlandi, Patrizia Alvisi, Paolo Lionetti   +8 more
wiley   +1 more source

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba, Carlos Walter Sobrado, Elizete Aparecida Lomazi, Mariana Deboni, Michela Cynthia da Rocha Marmo, Vanessa Adriana Scheeffer, Silvio da Rocha Carvalho, Adérson Omar Mourão Cintra Damião, Matheus Freitas Cardoso de Azevedo, Carlos Frederico Sparapan Marques, Eytan Wine, Artur Figueiredo Delgado, Clovis Artur Almeida da Silva Full   +12 more
wiley   +1 more source

Multiple Enteroenteric Fistulas- Crohn’s Disease- A Case Report

Iranian Journal of Public Health, 2015
Crohn's disease is a type of chronic inflammatory bowel disease (IBD) of unknown etiology that may affect any part of the gastrointestinal tract from mouth to anus and shows extra-intestinal involvement. It characteristically shows skip lesions.
Hasnain Abbas DHARAMSHI, Ali Abbas MOHSIN ALI, Tufail RAZA, Narmeen SHAHID, Faizan SHERAZ, Tooba SAJID, Zohair LILANI, Mustaqueem ur REHMAN, Taha NAFEES   +8 more
doaj  

Impact of 5‐ASA discontinuation in children with ulcerative colitis on biologic therapy: A propensity score‐matched study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives 5‐Aminosalicylic acid (5‐ASA) is recommended as a first‐line medication in mild to moderate ulcerative colitis (UC), but indications regarding its use in children with moderate to severe disease treated with biologics are lacking.
Giulia D'Arcangelo, Luca Scarallo, Giulia Mancuso, Mara Corpino, Claudio Romano, Lorenzo Norsa, Serena Arrigo, Matteo Bramuzzo, Maria Teresa Fioretti, Giovanna Zuin, Maria Teresa Illiceto, Paolo Lionetti, Marina Aloi   +12 more
wiley   +1 more source