Abstract Objectives Acute severe colitis (ASC) is a frequent and severe complication of ulcerative colitis (UC) with a high risk of colectomy. Effects of immunosuppressants and anti–tumor necrosis factor (anti‐TNF) agents on the risk of colectomy remain debated. We wished to study the evolution of French pediatric‐onset UC patients after ASC.
Manon Cochet +18 more
wiley +1 more source
Comparison of three magnetization transfer ratio parameters for assessment of intestinal fibrosis in patients with Crohn’s disease [PDF]
Feng, Shi-Ting +8 more
core +1 more source
Peptic ulcer disease: Insights and risk factors
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani +6 more
wiley +1 more source
Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley +1 more source
Successful treatment of therapy-resistant metastatic Crohn's desiase with infliximab [PDF]
CASTIGLIONE, FABIANA +5 more
core +1 more source
Ocular facial myositis and sialadenitis presenting with new onset ulcerative colitis
Abstract Extra‐intestinal manifestations of inflammatory bowel disease (IBD) can involve most organ systems, although the immunologic underpinnings are not well understood. Most patients who present with an extra‐intestinal manifestation have a single site of extra‐intestinal involvement; however, a small cohort presents with multiple different sites ...
Nicole Du, Nicole Mendez, Anil Darbari
wiley +1 more source
Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn’s disease [PDF]
Bonkowski, Erin +12 more
core +2 more sources
Successfully performed video capsule endoscopy in an 8‐month‐old infant weighing 7.5 kg
Abstract Video capsule endoscopy (VCE) is a well‐established diagnostic tool for examining the small bowel. Limited data exist on its use in infants. To our knowledge, we present the first detailed case of a successful PillCam®SB3‐VCE performed in an 8‐month‐old infant weighing 7.5 kg with suspected small bowel bleeding following allogeneic ...
Paul‐Christoph Zeisler +3 more
wiley +1 more source
A case report of Peutz–Jeghers syndrome in a child with Crohn's disease
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu +5 more
wiley +1 more source
Not all weight loss is psychiatric: Diagnostic bias in pediatric Crohn's disease
Abstract Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that can often be misdiagnosed, particularly in the female population. This is especially true in the initial stages, which are frequently characterized by weight loss and, at times, dietary intake restriction.
Karolina Aleksandra Jamrozik +7 more
wiley +1 more source

