Results 161 to 170 of about 88,864 (219)

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

External Genital Cutaneous Sarcoidosis Mimicking Lichen Sclerosus

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Although external genital cutaneous sarcoidosis is rare, it can closely resemble lichen sclerosus (LS) and delay diagnosis. We report a case of a 69‐year‐old woman with long‐standing vulvar symptoms and LS‐like pallor of the labia minora and clitoris. Biopsy showed non‐caseating granulomas with negative infection stains, consistent with vulvar
Enakshi Mudalige, Annabel Stevenson
wiley   +1 more source

Attentional variability as a cognitive marker of clinical activity in Crohn's disease. [PDF]

Crohns Colitis 360
Maia A, Schmidt JJ, Brandão Mello CE, Schmidt GJ, Tolentino YFM, Pires MMA, da Silva AC, Silva JDG, Sindorf ML, Schmidt SL.   +9 more
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil, Edward Roberts, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Reproducible ecological restructuring of the oral microbiome defines the oral-gut axis in Crohn’s disease

Whelan R, Wands D, Rimmer P, Hansen R, Wilson D, Moran G, Imai J, Hold G, Chapple I, Iqbal T, Gerasimidis K, Ho G.   +11 more
europepmc   +1 more source

Value of 3D‐High Resolution Anorectal Manometry Before and After Fistulotomy for Simple Perianal Fistulas: A Prospective Cohort Study

ANZ Journal of Surgery, EarlyView.
In this prospective cohort study, 3D‐high resolution anorectal manometry provided detailed regional pressure assessment but failed to predict postoperative continence deterioration after fistulotomy for simple perianal fistulas. These findings highlight the need for a continence assessment tool that better distinguishes true fecal incontinence from ...
Justin Y. van Oostendorp, Pieter van Hagen, Ruben Veldkamp, Lisette Dekker, Ingrid J. M. Han‐Geurts   +4 more
wiley   +1 more source

Diet, Ultra-Processed Foods, and Food Additives in Crohn's Disease: A Comprehensive Review. [PDF]

Nutrients
Flore G, Deledda A, Di Petrillo A.
europepmc   +1 more source