Results 161 to 170 of about 4,849,663 (241)
Abstract Objective To evaluate current international clinical practice in the assessment and management of rectal stump disease activity following colectomy in paediatric ulcerative colitis (UC). Methods A web‐based survey comprising 18 questions was distributed to paediatric gastroenterologists via European Porto inflammatory bowel disease (IBD ...
Beth Gordon +3 more
wiley +1 more source
Abstract Objectives To evaluate the outputs and clinical impact of a Cross‐Trust Histopathology Multidisciplinary Team (MDT) created to support diagnostic clarification and management of complex paediatric inflammatory bowel disease (IBD) cases, particularly during transition to adult services.
Valeria Dipasquale +5 more
wiley +1 more source
Abstract Objectives To evaluate the durability and predictors of loss of response of infliximab (IFX) over 2 years in paediatric Crohn's disease (CD) utilizing a proactive therapeutic drug monitoring (TDM) strategy. Methods A retrospective, single‐centre cohort study was conducted at The Children's Hospital at Westmead (CHW), Australia, from January ...
Cher Wei Chuah +9 more
wiley +1 more source
Abstract Objectives Adalimumab biosimilars are as safe and effective compared to the originator. Adult patients with inflammatory bowel disease (IBD) who switched to a biosimilar have comparable outcomes, but pediatric data are limited. This study evaluates clinical outcomes of children and young adults with IBD following a nonmedical, insurance‐driven
Daniel Himelstein +5 more
wiley +1 more source
Abstract Paediatric inflammatory bowel disease (pIBD) is a long‐term, immune‐mediated condition characterised by fluctuating gastrointestinal symptoms, nutritional risk and psychosocial difficulties. Although multidisciplinary team (MDT) support is considered the gold standard, there is considerable variation in how it is delivered, and it remains ...
King‐Chi Yau, Laura Tesser, Kay Crook
wiley +1 more source
Hair loss in pediatric inflammatory bowel disease: Clinical recognition and implications for care
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Angela Anaeme +2 more
wiley +1 more source
Abstract Objectives Monogenic causes of congenital diarrheas and enteropathies (CoDE) and very early onset inflammatory bowel disease (VEOIBD) are mostly recessive and therefore more prevalent in populations with increased consanguinity rates. To assess the genetic basis of these disorders in a likely high‐prevalence population, we established a multi ...
Lily Gillette +21 more
wiley +1 more source
Abstract The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) recognized the need to define research priorities and identify knowledge gaps to guide future investigations in pediatric digestive health. Following international examples, SIGENP aimed to provide a structured framework that aligns scientific innovation with ...
Carlo Agostoni +46 more
wiley +1 more source
Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche +8 more
wiley +1 more source
The ImproveCareNow Registry: Prediction of different remission rates in pediatric ulcerative colitis
Abstract Objectives Identifying predictors of clinical remission in pediatric ulcerative colitis (UC) will impact the therapeutic approach. We aimed to predict time to first (TFR), corticosteroid‐free (TCSFR, ≥3 months corticosteroid withdrawal), and sustained remission (TSR, ≥6 months).
Jonathan Van Hecke +7 more
wiley +1 more source

