Results 151 to 160 of about 10,462,861 (343)

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Medical treatment of perianal crohn disease

The Saudi Journal of Gastroenterology, 2002
Crohn disease is a chronic illness that affects the gastrointestinal tract from the mouth to the anus. Perianal Crohn develops in 31-94% of patients over the course of their illness. It affects the skin in the perianal area, the anal canal and can
Al-Ghamdi Abdullah
doaj  

Measuring disease activity in Crohn's disease: what is currently available to the clinician

, 2014
Renata D'Incà, Roberta Caccaro Department of Surgical, Oncological and Gastroenterological Sciences, Gastroenterology Section, University of Padua, Padua, Italy Abstract: Crohn's disease (CD) is a chronic inflammatory bowel disease ...
Caccaro R, D’Incà R
core  

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Profile of infliximab in the treatment of pediatric Crohn’s disease

Pediatric Health, Medicine and Therapeutics, 2015
Jaroslaw Kierkus,1 Edyta Szymanska,2 Grzegorz Oracz,1 Anna Wiernicka,1 Maciej Dadalski1 1Department of Gastroenterology, Hepatology, Feeding Disorders and Pediatrics, 2Department of Pediatrics, Nutrition and Metabolic Disorders, The Children’s ...
Kierus J, Szymanska E, Oracz G, Wiernicka A, Dadalski M   +4 more
doaj  

PERANAN DUAL ENERGY PADA CT ENTEROGRAFI DENGAN KLINIS CROHN DISEASE

, 2021
Pemeriksaan CT enterografi merupakan pemeriksaan khusus untuk memperlihatkan gangguan pada small intestines terutama crohn disease, namun adanya lemak dan perdarahan intramural dapat mengakibatkan kesalahan dalam menilai tingkat enchancement intestines ...
Marichatul Jannah, Yeti Kartikasari, NOFA ROSALINA   +2 more
core  

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

Crohn Disease [PDF]

JAMA, 2008
openaire   +2 more sources

3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1 Diagnosis and Medical Management

Journal of Crohn's & Colitis, 2017
F. Gomollón, A. Dignass, V. Annese, H. Tilg, G. Van Assche, J. Lindsay, L. Peyrin-Biroulet, G. Cullen, M. Daperno, T. Kucharzik, Florian Rieder, S. Almér, A. Armuzzi, M. Harbord, J. Langhorst, M. Sans, Y. Chowers, G. Fiorino, P. Juillerat, G. Mantzaris, F. Rizzello, S. Vavricka, P. Gionchetti   +22 more
semanticscholar   +1 more source