Results 131 to 140 of about 15,981,489 (330)
International Journal of Cancer, EarlyView.Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia +4 more
wiley +1 more source
Clinical and Experimental Gastroenterology, 2017 Aranzazu Jauregui-Amezaga, Michael Somers, Heiko De Schepper, Elisabeth Macken Department of Gastroenterology, Universitair Ziekenhuis Antwerpen, University of Antwerp, Antwerp, Belgium Abstract: The limited efficacy of the currently ...
Jauregui-Amezaga A +3 more
doaj
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
, 1985 During the past 2 years, we have encountered 14 patients whose onset of clinical symptoms of Crohn disease occurred after the age of 50, accounting for 14% of all Crohn disease patients studied in our department during this period.
Ackerman, L V +3 more
core +1 more source
iMetaMed, EarlyView.Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang +6 more
wiley +1 more source
, 2014 Crohn disease is an idiopathic, chronic inflammatory disorder of the bowel, involving any region of the gastrointestinal tract from the mouth to anus.
Navam Kumarasinghe, Ra Abeysekera
core
iNew Medicine, EarlyView.ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang +9 more
wiley +1 more source
Measuring disease activity in Crohn's disease: what is currently available to the clinician
, 2014 Renata D'Incà, Roberta Caccaro Department of Surgical, Oncological and Gastroenterological Sciences, Gastroenterology Section, University of Padua, Padua, Italy Abstract: Crohn's disease (CD) is a chronic inflammatory bowel disease ...
Caccaro R, D’Incà R
core
Journal of Applied Toxicology, EarlyView.ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati +6 more
wiley +1 more source
Journal of Hospital Medicine, EarlyView.Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile. Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a ...
David Wong Arias +2 more
wiley +1 more source