Results 111 to 120 of about 15,981,489 (330)

Cutaneous manifestations of metastatic Crohn\u27s disease

, 2018
Metastatic Crohn\u27s disease is a rare cutaneous complication of primary Crohn\u27s disease. It is a granulomatous inflammatory process, similar to the pathogenic mechanism of Crohn\u27s disease, that occurs in sites discontiguous from the ...
Foster, Katherine, Schneider, Samantha L, Shwayder, Tor, Patel, Devika   +3 more
core   +1 more source

An evidence-based review of natalizumab therapy in the management of Crohn’s disease

Therapeutics and Clinical Risk Management, 2009
Raja GR Edula, Michael F PiccoMayo Clinic, Jacksonville, Florida, USAAbstract: Treatment options for Crohn’s disease have evolved beyond the early goals of induction and remission and are now more focused on preventing complications by altering
Raja GR Edula, Michael F Picco
doaj  

Radiologic, Histologic and Scanning Electron Microscopic Characterization of the Peritoneal Reflection in Crohn's Disease

Clinical Anatomy, EarlyView.
ABSTRACT The peritoneal reflection bridges visceral and parietal peritoneum and lacks adjoining or underlying organs. As such it provides an opportunity to perform a focussed examination of the peritoneum in Crohn's disease. The aim of this study was to exploit this anatomical property and conduct a multilayered, focussed examination of the peritoneal ...
L. Walsh, D. Walsh, C. P. Dunne, P. Dockery, J. C. Coffey   +4 more
wiley   +1 more source

Inclusion of the Mesentery in Ileocolic Resection for Crohn’s Disease is Associated With Reduced Surgical Recurrence

Journal of Crohn's & Colitis, 2018
Background and Aims Inclusion of the mesentery during resection for colorectal cancer is associated with improved outcomes but has yet to be evaluated in Crohn’s disease.
C. Coffey, M. Kiernan, S. Sahebally, A. Jarrar, J. Burke, P. Kiely, B. Shen, D. Waldron, C. Peirce, M. Moloney, M. Skelly, P. Tibbitts, H. Hidayat, P. Faul, V. Healy, P. O'leary, L. Walsh, P. Dockery, R. O'Connell, Seán T. Martin, F. Shanahan, C. Fiocchi, C. Dunne   +22 more
semanticscholar   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Crohn's disease in women.

International journal of women's health, 2013
This article provides an overview of the obstetric and gynecological manifestations of Crohn's disease (CD). High incidence of the new onset of the disease in young women in their reproductive years demands special concern from physicians involved in their treatment.
Plavšić, Ivana, Štimac, Tea, Hauser, Goran   +2 more
openaire   +4 more sources

Patients with Chronic Inflammatory Diseases Can Experience Higher Exposure of Small Molecule Drugs than Healthy Volunteers: An Analysis of Recently Approved Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Chronic inflammation has long been known to downregulate the activity of certain cytochrome P450 (CYP) enzymes—the main enzymes responsible for the phase I metabolism of many small molecule drugs—potentially leading to higher exposures in patients with chronic inflammatory diseases compared to healthy volunteers. Neglecting this potential difference in
Johannes Tillil, Sathej Gopalakrishnan, Jennifer Dong, Karthik Venkatakrishnan, Charlotte Kloft, Wilhelm Huisinga, Lena Klopp‐Schulze   +6 more
wiley   +1 more source

A Case of genitourinary Crohn\u27s disease

, 2012
Scrotal swelling in young boys is a common problem. The differential diagnosis includes testicular torsion, epididymoorchitis, and idiopathic scrotal edema.
Weinberg, Aviva E., Hsieh, Michael H., Hazard, Florette K.   +2 more
core   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source