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Current Problems in Surgery, 1993
The clinical and pathological description of Crohn’s disease (CD) in 1932 described inflammation of the terminal ileum (1). It was not until 1959, 100 yr after Samuel Wilks described ulcerative colitis (UC), that variants of CD were recognized to potentially, or exclusively, involve the colon (2).
G E, Block +4 more
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The clinical and pathological description of Crohn’s disease (CD) in 1932 described inflammation of the terminal ileum (1). It was not until 1959, 100 yr after Samuel Wilks described ulcerative colitis (UC), that variants of CD were recognized to potentially, or exclusively, involve the colon (2).
G E, Block +4 more
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Medicina Clínica (English Edition), 2018
Crohn's disease is a chronic inflammatory bowel disease of unknown etiology associated with an impaired immune response, with periods of activity and remission. It is characterised by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea,
María Pilar, Ballester Ferré +2 more
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Crohn's disease is a chronic inflammatory bowel disease of unknown etiology associated with an impaired immune response, with periods of activity and remission. It is characterised by patchy and transmural lesions which can affect the entire gastrointestinal tract, from the mouth to the anus. The most frequent symptoms are abdominal pain and diarrhoea,
María Pilar, Ballester Ferré +2 more
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The Lancet
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
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Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract that might lead to progressive bowel damage and disability. The exact cause of Crohn's disease is unknown, but evidence points towards multifactorial events causing dysregulation of the innate immune system in genetically susceptible people.
Dolinger, Michael +2 more
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The Lancet, 2017
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with increasing incidence worldwide. Crohn's disease might result from a complex interplay between genetic susceptibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adaptive immune responses.
Torres, Joana +3 more
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Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with increasing incidence worldwide. Crohn's disease might result from a complex interplay between genetic susceptibility, environmental factors, and altered gut microbiota, leading to dysregulated innate and adaptive immune responses.
Torres, Joana +3 more
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The Indian Journal of Pediatrics, 2006
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract and is an important cause of morbidity in children and adolescents. In India Crohn's disease (CD) was considered a rare disease, however, during the last 10 years CD in adults is being reported from several centers especially in Southern India.
Malathi, Sathiyasekaran, So, Shivbalan
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Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract and is an important cause of morbidity in children and adolescents. In India Crohn's disease (CD) was considered a rare disease, however, during the last 10 years CD in adults is being reported from several centers especially in Southern India.
Malathi, Sathiyasekaran, So, Shivbalan
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The Lancet, 2002
Crohn's disease is a disorder mediated by T lymphocytes which arises in genetically susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria. Regulation of immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and ...
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Crohn's disease is a disorder mediated by T lymphocytes which arises in genetically susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria. Regulation of immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and ...
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Current Drug Targets, 2012
Over the past few years, the technical evolution of ultrasound equipment, the use of oral and intravenous contrast agents, and an increase in the expertise of sonographers has enhanced the role of ultrasonography that plays in the assessment of the gastrointestinal tract. In chronic inflammatory conditions, primarily CD, this technology can be used not
CALABRESE, EMMA +2 more
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Over the past few years, the technical evolution of ultrasound equipment, the use of oral and intravenous contrast agents, and an increase in the expertise of sonographers has enhanced the role of ultrasonography that plays in the assessment of the gastrointestinal tract. In chronic inflammatory conditions, primarily CD, this technology can be used not
CALABRESE, EMMA +2 more
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Archives of Surgery, 1976
Seventy-eight women with Crohn disease, each having the physical capability and opportunity to bear children, were admitted to the New York Hospital-Cornell Medical Center during a 20-year period. Forty-two pregnancies occurred. Results are suggestive of overall decreased fertility with no significant difference according to site of disease.
W P, Homan, B, Thorbjarnarson
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Seventy-eight women with Crohn disease, each having the physical capability and opportunity to bear children, were admitted to the New York Hospital-Cornell Medical Center during a 20-year period. Forty-two pregnancies occurred. Results are suggestive of overall decreased fertility with no significant difference according to site of disease.
W P, Homan, B, Thorbjarnarson
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The dilemma of Crohn's disease
Diseases of the Colon & Rectum, 1977The results of our clinical study, generally supported by the recent literature and a consensus of colorectal surgeons, indicate that an appendectomy can safely be performed in the presence of Crohn's ileitis. When fistulas do occur, they originate in the small bowel and not in the appendiceal stump.
P, Kovalcik +3 more
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