Results 261 to 270 of about 10,462,861 (343)

One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard   +13 more
wiley   +1 more source

A Care Pathway for the Treatment of IBD Reduces Healthcare Costs and Is Cost‐Effective: Results of the Multicentre IBD Value Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This study provides real‐world evidence that implementing an advanced therapy care pathway for patients with IBD leads to significant healthcare cost savings without compromising quality of life. These findings support broader implementation of care pathways in the management of patients with chronic conditions to optimise care delivery and resource ...
Elyke H. Visser   +12 more
wiley   +1 more source

Clinical Trial: Predicting Response to Iron Therapy in Patients With Active Inflammatory Bowel Disease Using Hepcidin and Functional Iron Indices: A Multicentre Randomised Trial

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Hepcidin levels predict response to iron therapy and support route selection for iron therapy in patients with active inflammatory bowel disease: higher levels favour IV iron, while lower levels indicate likely oral response. Ferritin‐based indices, particularly transferrin/log10(ferritin) and sTfR/log10(ferritin), offer reliable alternatives. ABSTRACT
Lola J. M. Koppelman   +14 more
wiley   +1 more source

Reliability of CT Enterography for Describing Fibrostenosing Crohn Disease. [PDF]

open access: yesRadiology
Rieder F   +20 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Pediatric Crohn Disease Presenting as Isolated Acute Upper-GI Bleed: A Case Report. [PDF]

open access: yesAm J Case Rep
Norris L   +8 more
europepmc   +1 more source

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