Results 251 to 260 of about 10,462,861 (343)

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Transperineal Ultrasound-Guided Endoscopic Sinusotomy for Recurrent Perianal Sinus in Crohn Disease. [PDF]

ACG Case Rep J
Pal P, Mateen MA, Gupta R, Tandan M, Reddy DN.   +4 more
europepmc   +1 more source

Changing Aetiology of Perforated Peptic Ulcers: Rising Impact of Non‐Steroidal‐Anti‐Inflammatories in Western Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Peptic ulcer disease (PUD) continues to be a health issue, mainly due to Helicobacter pylori (H. pylori) infection and non‐steroidal anti‐inflammatory drugs (NSAIDs). Despite better treatment of H. pylori and use of proton pump inhibitors, the rate of reduction in PUD complications is slowing down.
Vidya Willis, Tamalee Wilson, David R. Fletcher, Amanda J. Foster   +3 more
wiley   +1 more source

Stomal calprotectin as a biomarker for assessing Crohn disease activity in patients with stomas. [PDF]

Intern Med J
Abeyratne K, Harb M, Bensted K, Ghaly S, Connor SJ, Andrews JM, Lynch KD.   +6 more
europepmc   +1 more source

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil, Edward Roberts, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease

Pediatric Investigation, EarlyView.
Mei Kamidani, Ryo Tanaka, Hiroshi Oue, Risa Fukuda, Rena Hashimoto, Ichiro Takeuchi, Takako Yoshioka, Naoya Tonegawa, Akira Ishiguro, Katsuhiro Arai, Kazue Yoshida   +10 more
wiley   +1 more source

Self‐reported pelvic floor dysfunction 12 months after an obstetric anal sphincter injury in relation to maternal body mass index

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Self‐reported dyspareunia one year after an obstetric anal sphincter injury (OASI) is less common among overweight and obese women than in normal weight. The risk for anal incontinence does not differ between the BMI groups one year after an OASI, while the risk for UI increases with increasing BMI.
Linda Hjertberg, Eva Uustal, Marie Blomberg, Sofia Pihl   +3 more
wiley   +1 more source

First Reported Successful Use of Infliximab Maintenance Therapy for Dual Treatment of Crohn Disease and Idiopathic Retroperitoneal Fibrosis. [PDF]

ACG Case Rep J
Isaac-Coss G, Post Z, Kakarla M, Johnsky L, Sakuraba A, Miller I, Shriram JM, Frasca J.   +7 more
europepmc   +1 more source

Pelvic floor symptoms and quality of life 1 year postpartum in Swedish primiparous women—A follow‐up of a randomized controlled trial

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this follow‐up of a randomized controlled trial including 1911 primiparous women with a vaginal birth, minor and major second‐degree tears were not associated with pelvic floor dysfunction 1 year postpartum. OASI was associated with colorectal–anal symptoms, whereas episiotomy was associated with vaginal symptoms affecting body image.
Malin Edqvist, Cecilia Häggsgård, Pia Teleman, Gunilla Tegerstedt, Gunilla Ajne, Susann Ullén, Helena Tern, Karin Ängeby, Hannah G. Dahlen, Christine Rubertsson   +9 more
wiley   +1 more source

The impact of systemic long‐term medications for the development of age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä, Reijo Sund, Toni Rikkonen, Kai Kaarniranta   +3 more
wiley   +1 more source