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Cromolyn Sodium in Childhood Asthma
Hospital Practice, 1974Clinical trials have shown that this agent decreases frequency of asthmatic attacks, makes possible reduced concomitant medication, and improves pulmonary function and other parameters of childhood asthma in about four fifths of patients. But it is a prophylactic, not a symptomatic treatment, and does not abolish the need to determine the source of the
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Detrimental effects of hypotonic cromolyn sodium
The Journal of Pediatrics, 1992In a randomized, double-blind, placebo-controlled, crossover study, inhalation of the commercially available nebulized form of cromolyn sodium resulted in a significant decrease in forced midexpiratory flow rate between the 25th and 75th percentile points, equivalent to that observed for distilled water, in children with chronic asthma.
Gary S. Rachelefsky +3 more
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Cromolyn Sodium in the Treatment of Ulcerative Colitis
Journal of Clinical Gastroenterology, 1980An immediate hypersensitivity reaction with mast cell degranulation may be of importance in the pathogenesis of ulcerative colitis. Cromolyn sodium stabilizes the mast cell membrane, and thus could have potential benefit in the treatment of this disease. The few clinical studies published to date are difficult to interpret, and have not established the
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Cromolyn sodium: A potential therapy for uremic pruritus?
Hemodialysis International, 2006AbstractUremic pruritus occurs in up to 50% of patients undergoing chronic hemodialysis. The pathogenesis of this disabling condition is unknown but likely involves multiple pathways involving the peripheral and central nervous system as well as local chemical and inflammatory mediators.
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Cromolyn sodium in ocular allergic diseases.
Journal of the American Optometric Association, 1986Cromolyn sodium is a highly effective topical anti-allergenic solution for the treatment of vernal, giant papillary, ragweed, and atopic conjunctivitis. It acts by inhibiting the release of histamine and thereby prevents the inflammatory response by subacute type I hypersensitivity reactions.
T M, Goen, K, Sieboldt, J E, Terry
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