Results 131 to 140 of about 109,619 (308)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Assessing Crop Damage from Wind, Hail and Flooding

, 2014
Storms this past week have resulted in hail, wind and flooding damage across the state. Damage to both corn and soybean crops range from extensive defoliation to root lodging.
Licht, Mark
core  

Weather and corn: Crop condition reports are not enough

, 2010
Drought, hail, frost, flood, and heat waves, together with impacts of soil fertility and moisture, weed pressure, insect damage, and plant disease are in the group of environmental factors that impact the reported crop condition and, ultimately, crop ...
Taylor, Elwynn, Elwynn Taylor
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Friend or foe? Attitudes of rice farmers toward wild animals in West Africa

Ecology and Society
As the global human population grows and the demand for space and resources increases, human-wildlife interactions and conflicts are expected to rise, particularly in biodiversity-rich tropical agroecosystems where subsistence farmers and wildlife ...
Patrícia Chaves, Marije Schaafsma, Djunco Dabo, Judite Z. Lomba, Fode Mane, Ricardo F. de Lima, Jorge M. Palmeirim, Ricardo Rocha, Sambu Seck, Justino Biai, Sérgio Timóteo, Christoph F. J. Meyer, Ana Rainho   +12 more
doaj   +1 more source

Plan for 2009 Crop Year by Managing Flooded Soils

, 2008
Approximately 1.2 million acres of Iowa farm land affected by flooding early this year have not been planted to any crop. There are potential economic and soil environmental consequences of leaving these soils unattended. The long-term damage to soil and
Barnhart, Stephen, Al-Kaisi, Mahdi
core  

Planning for Deer-Hunting Management at the Local and Regional Scales: Reconciling Economic, Social and Ecological Functions

Land
Game species with home ranges exceeding the area of the management units may entail conflicts over hunting rights and cause damage to crops and forest stands in surrounding areas.
Cláudio Bicho, Rui Machado, Russell Alpizar-Jara, Pedro Santos   +3 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Multimodal Data‐Driven Microstructure Characterization

Advanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang, Santiago Benito, Özge Özgün, Sebastian Weber, Markus Stricker   +4 more
wiley   +1 more source

Soft Mechanical‐Electrical Logic Using Liquid Metal‐Filled 3D‐Printed Architectures

Advanced Engineering Materials, EarlyView.
We present 3D‐printed soft mechanical–electrical logic elements that use liquid metal–filled silicone tubes actuated by thermoplastic polyurethane/polylactic acid (TPU/PLA) architectures to produce Boolean operations. Complementary normally open and normally closed unit cells perform repeatable binary transitions and can be combined into more complex ...
Christoph Lehmann, Ryan Kalgreen, Laura M. Comella   +2 more
wiley   +1 more source