Results 71 to 80 of about 1,050,820 (318)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Nitrogen Fertilization Increases Root Growth and Coordinates the Root–Shoot Relationship in Cotton

Frontiers in Plant Science, 2020
The root system plays an important role in the growth and development of cotton, and root growth is closely related to shoot growth, both of which are affected by N availability in the soil.
Jing Chen, Jing Chen, Liantao Liu, Zhanbiao Wang, Zhanbiao Wang, Yongjiang Zhang, Hongchun Sun, Shijia Song, Zhiying Bai, Zhanyuan Lu, Cundong Li   +10 more
doaj   +1 more source

The application of time-series MODIS NDVI profiles for the acquisition of crop information across Afghanistan [PDF]

, 2014
We investigated and developed a prototype crop information system integrating 250 m Moderate Resolution Imaging Spectroradiometer (MODIS) normalized difference vegetation index (NDVI) data with other available remotely sensed imagery, field data, and ...
Juniper, Graham R., Simms, Daniel M., Taylor, John C., Waine, Toby W.   +3 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Effects of iron tailings on the growth and physiological response of cool-season turfgrass

Grass Research
Over the past few decades, due to mining activity, a large amount of iron mine tailing sands have been deposited. Selection of appropriate plant species and studying their growth and physiological response under iron tailings are the key factors for ...
Ran Chen, Yuchan Zhu, Weikuo Han, Lu Chen, Xinru Guo, Xinyao Jin, Hanrui Li, Miao Jin, Lin Li, Chuntong Li, Yue Chen, Xinbo Sun   +11 more
doaj   +1 more source

AsHSP26.8a, a creeping bentgrass small heat shock protein integrates different signaling pathways to modulate plant abiotic stress response

BMC Plant Biology, 2020
Background Small heat shock proteins (sHSPs) are critical for plant response to biotic and abiotic stresses, especially heat stress. They have also been implicated in various aspects of plant development.
Xinbo Sun, Junfei Zhu, Xin Li, Zhigang Li, Liebao Han, Hong Luo   +5 more
doaj   +1 more source

Competitiveness of winter wheat stands against weeds: Effects of cultivar choice, row width and drilling direction [PDF]

, 2002
The need for competitive crop stands can be regarded as a basic requirement for weed control, potentially reducing the need for direct control measures. One way the crop may suppress weed growth is by the restriction of light through crop shading.
Drews, Sylvia, Juroszek, Peter, Köpke, Ulrich, Neuhoff, Daniel   +3 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Growth and ripening of main-crop fig.

Advances in horticultural science, 1992
The main crop of the «common» type fig cv. 'Rampelina' exhibited a three-stage growth cycle: two periods of rapid development interrupted by a slow growth phase; the climacteric and the increase in ethylene occurred in the latter rapid stage. The compositional and physiological changes marking fruit development were recorded in fruits divided by ...
CHESSA I., NIEDDU, Giovanni, SCHIRRA M.
openaire   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source