Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Management of Plant Growth Regulators in Cotton Using Active Crop Canopy Sensors
Factors affecting cotton development present spatial and temporal variability. Plant growth regulators (PGR) are used to control vegetative growth, promote higher yields, better fiber quality, and facilitate mechanical harvest.
Rodrigo Gonçalves Trevisan +3 more
doaj +1 more source
Effect of Different Intercropping Ratios of Three Bean Ecotypes as Replacement Series on their Physiological Indices [PDF]
Introduction Recently self-sustaining, diversified, low-input, and energy-efficient agricultural systems like intercropping have been considered as the efficient way to achieve the sustainability in agriculture.
Y Rameshjan +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Evaluation of Volunteer Barley Interference on Growth Indices of Some Wheat CultivarsCultivars
To evaluate interference effects of volunteer barley on growth indices of six wheat cultivars, a study conducted in Sabzevar region during 2007-2008 growing season.
H. Ramyar, M. Jamnajad
doaj +1 more source
Soybean Yield Formation Physiology – A Foundation for Precision Breeding Based Improvement
The continued improvement of crop yield is a fundamental driver in agriculture and is the goal of both plant breeders and researchers. Plant breeders have been remarkably successful in improving crop yield, as demonstrated by the continued release of ...
Jonathan T. Vogel +5 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Growth Dynamic of Sugarcane Cultivars C97-366 and C99-374 for Forage Production
Context: Plant growth analysis is a valuable tool to detect biomass formation and accumulation. The determination of growth indexes enables plants to adapt to different edaphoclimatic conditions, and to select the most promising responses among them ...
Yoslen Fernández Gálvez +5 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

